Supplementary data for '3D printed spherical mini-tablets: geometry versus composition effects in controlling dissolution from personalised solid dosage forms'.

  • Sejad Ayyoubi (Creator)
  • Jose R Cerda (Creator)
  • Raquel Fernandez-Garcia (Creator)
  • Peter Knief (Creator)
  • Katerina Lalatsa (Creator)
  • Anne Marie Healy (Creator)
  • Dolores Remedios Serrano Lopez (Creator)



Table S1. Characteristics of the in-house manufactured filaments and mini-tablets.
Table S2. The fraction of crystalline NFD within the mini-tablets derived from the heat of fusion taking into account the amount of NFD within the formulation. BQL: below the quantification limit.
Table S3. Glass transition temperatures for raw KV64, raw EC and 3D printed mini-tablets calculated from the reversed heat flow DSC thermograms.
Table S4. Dissolution modelling data

Figure S1. PXRD analysis of the surface of the EC-based mini-tablets
Figure S2. DSC reverse heat flow thermograms of the raw materials, physical mixtures, filaments and 3D printed mini-tablets
Figure S3. Drug-release profiles for the EC50 and cpEC50 formulations.
Figure S4. PLS prediction model of NFD release.
Date made available15 Feb 2021
PublisherUniversity of Portsmouth

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