Research outputs per year
Research outputs per year
Organisation profile
Organisation profile
At the Centre for Enzyme Innovation, we are working to solve one of the most pressing environmental issues facing our planet.
Learning from the natural world, we are delivering transformative enzyme-enabled solutions for the circular recycling of plastics.
Following a £5.8 million award from the Research England Expanding Excellence Fund in 2019, and a £1m award from the Solent Local Enterprise Partnership in 2020 through the HM Government Getting Building Fund, we have created state-of-the-art facilities and built a team of specialist multidiscipline researchers to deliver world-class research and innovation.
We currently have 30 scientists covering a wide range of disciplines including microbiology, molecular biophysics, biochemistry, enzyme engineering and synthetic biology, biotechnology, and more recently, polymer chemistry.
Hosted in our new custom laboratories, we have the expertise and facilities required to help tackle the challenge of plastic pollution and develop enzyme-based low energy, low carbon, biorecycling solutions.
Our research sits at the interface between enzymes and polymers with a focus on both pure and applied research in biocatalysis.
We are expanding our research and innovation activities to address the diverse range of plastics, including mixed waste streams and composites, materials that are often incinerated or end up in landfill and leak to the environment.
Our research is divided into 4 areas:
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Discover new enzymes from the environment that break down plastics
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Engineer these enzymes to enhance their activity, stability and yield
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Deploy enzymes by pilot scale fermentation and industry-ready formulations
- Apply these enzymes in proof-of-concept biorecycling and upcycling processes
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. Our work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Angie Beckett
- Faculty of Science & Health, School of Biological Sciences - Specialist Technician (Research)
- Centre for Enzyme Innovation
- Institute of Biomedical & Biomolecular Sciences
Person: Support
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Victoria Bemmer
- Faculty of Science & Health, School of Biological Sciences - Senior Research Fellow
- Centre for Enzyme Innovation
- Institute of Biomedical & Biomolecular Sciences
Person: Research, Academic
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Jessica Berrones Reyes
- Faculty of Science & Health, School of Biological Sciences - Senior Research Associate
- Centre for Enzyme Innovation
Person: Research
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Biochemical and structural characterization of a Sphingomonas diarylpropane lyase for cofactorless deformylation
Kuatsjah, E., Zahn, M., Chen, X., Kato, R., Hinchen, D. J., Konev, M., Katahira, R., Orr, C., Wagner, A., Zou, Y., Haugen, S. J., Ramirez, K., Michener, J. K., Pickford, A., Kamimura, N., Masai, E., Houk, K. N., McGeehan, J. & Beckham, G. T., 18 Jan 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 4, 9 p., e2212246120.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Downloads (Pure) -
Cardiac competence of the paraxial head mesoderm fades concomitant with a shift towards the head skeletal muscle programme
Alzamrooni, A. M. A. M., Mendes Vieira, P., Murciano, N., Wolton, M., Schubert, F., Robson, S. & Dietrich, S., 1 Sept 2023, In: Developmental Biology. 501, p. 39-59 21 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Downloads (Pure) -
Combining theoretical and experimental methods to probe confinement within microporous solid acid catalysts for alcohol dehydration
Potter, M. E., Amsler, J., Spiske, L., Plessow, P. N., Asare, T., Carravetta, M., Raja, R., Cox, P. A., Studt, F. & Armstrong, L-M., 5 May 2023, In: ACS Catalysis. 13, 9, p. 5955-5968Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Downloads (Pure)
Student theses
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Aspects of the life history strategies of the Teredinidae
Author: Shipway, R., Sept 2013Supervisor: Cragg, S. (Supervisor) & Ford, A. (Supervisor)
Student thesis: Doctoral Thesis
File
Datasets
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Site-Specific Iron Substitution in STA-28, a Large Pore Aluminophosphate Zeotype prepared using 1,10-Phenanthrolines as Framework-Bound Structure Directing Agents (dataset)
Shannon, M. D. (Creator), Dugulan, A. I. (Creator), Wright, P. A. (Creator), Dawson, D. M. (Creator), Lozinska, M. M. (Creator), Ashbrook, S. E. M. (Creator), Cox, P. (Creator), Bode, B. E. (Creator), Slawin, A. M. Z. (Creator), Mayoral, A. (Creator), Watts, A. E. (Creator) & Turrina, A. (Creator), University of St Andrews, 1 Jan 2020
DOI: 10.17630/89249deb-fdde-466b-934b-902a987f6fed, https://risweb.st-andrews.ac.uk/portal/en/datasets/sitespecific-iron-substitution-in-sta28-a-large-pore-aluminophosphate-zeotype-prepared-using-110phenanthrolines-as-frameworkbound-structure-directing-agents-dataset(89249deb-fdde-466b-934b-902a987f6fed).html
Dataset
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The role of Bmp and Fgf signalling in early embryonic head development
Schubert, F. (Creator), Robson, S. (Creator) & Dietrich, S. (Creator), NCBI, 8 May 2023
DOI: https://www.ncbi.nlm.nih.gov/bioproject/970268, https://www.ncbi.nlm.nih.gov/bioproject/970268
Dataset
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CoMic: Correlative Multimodal Microscopy for Marine Invertebrates
Wood, C., Hughes, L., Cragg, S., Shipway, R., Bemmer, V., Machado, P. & Martin, L.
1/12/20 → …
Project: Research
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CEI: Centre for Enzymes Innovation (CEI) Expansion
Pickford, A., Duckering, S., Miles, R., Lichtenstein, B. & McGeehan, J.
12/11/20 → …
Project: Research
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New enzymes for degrading natural and synthetic polymers: A combined structural and synthetic biology approach
Pickford, A. & McGeehan, J.
1/10/18 → 30/09/23
Project: Research
Activities
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Introduction to the News Media
Sam Robson (Participant)
20 Sept 2023Activity: Participating in or organising an event types › Participation in workshop, seminar, course
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GRIPS 2023: The transition to Plastics Circularity
Andrew Pickford (Participant)
10 May 2023 → 11 May 2023Activity: Participating in or organising an event types › Participation in conference
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Panel Member - Oxford Grand Challenges "Plastic Crisis"
Andrew Pickford (Invited speaker)
5 May 2023Activity: Talk or presentation types › Invited talk
Prizes
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Best Poster Award
Oliveira Pessoa, Liliana (Recipient), Nov 2022
Prize: Prize (including medals and awards)
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Conference Attendance Grant
Oliveira Pessoa, Liliana (Recipient), Mar 2023
Prize: Prize (including medals and awards)
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Researcher Development and Travel Grant
Oliveira Pessoa, Liliana (Recipient), May 2023
Prize: Prize (including medals and awards)
Press/Media
Equipment
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AKTA Pure Column Chromatography
Bruce Lichtenstein (Manager)
School of Biological SciencesFacility/equipment: Equipment
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Applikon Bioreactor Array
Elaine Rudge (Manager)
School of Biological SciencesFacility/equipment: Equipment
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ArrayIT SpotBot HotBed array spotter
Victoria Bemmer (Manager)
School of Biological SciencesFacility/equipment: Equipment