Institute of Life Sciences and Healthcare

2006

Structural insight into binding of Staphylococcus aureus to human fibronectin

Pilka, E., Werner, J., Schwarz-Linek, U., Pickford, A., Meenan, N., Campbell, I. & Potts, J., 2006, In: FEBS Letters. 580, 1, p. 273-277 5 p.

Research output: Contribution to journal › Article › peer-review

Structure of the neuronal protein calexcitin suggests a mode of interaction in signalling pathways of learning and memory

Erskine, P. T., Beaven, G. D. E., Hagan, R., Findlow, I. S., Werner, J. M., Wood, S. P., Vernon, J., Giese, K. P., Fox, G. C. & Cooper, J. B., 1 Apr 2006, In: Journal of Molecular Biology. 357, 5, p. 1536-1547

Research output: Contribution to journal › Article › peer-review

Open Access

Targeting C-reactive protein for the treatment of cardiovascular disease

Pepys, M. B., Hirschfield, G. M., Tennent, G. A., Gallimore, J. R., Kahan, M. C., Bellotti, V., Hawkins, P. N., Myers, R. M., Smith, M. D., Polara, A., Cobb, A. J. A., Ley, S. V., Aquilina, J. A., Robinson, C. V., Sharif, I., Gray, G. A., Sabin, C. A., Jenvey, M. C., Kolstoe, S. E., Thompson, D., & 1 othersWood, S. P., 27 Apr 2006, In: Nature. 440, 7088, p. 1217-21

Research output: Contribution to journal › Article › peer-review

The effectiveness of environmental enrichment on reducing stereotypic behaviour in two captive vicugna (Vicugna vicugna)

Parker, M., Goodwin, D., Redhead, E. & Mitchell, H., 1 Feb 2006, In: Animal Welfare. 15, 1, p. 59-62 4 p.

Research output: Contribution to journal › Article › peer-review

The Forkhead box M1 protein regulates the transcription of the estrogen receptor alpha in breast cancer cells

Madureira, P. A., Varshochi, R., Constantinidou, D., Francis, R. E., Coombes, R. C., Yao, K-M. & Lam, E. W-F., 1 Sept 2006, In: The Journal of Biological Chemistry. 281, 35, p. 25167-25176 10 p.

Research output: Contribution to journal › Article › peer-review

The study of strictly anaerobic microorganisms

Sowers, K. R. & Watts, J. E. M., 1 Dec 2006, Methods in Microbiology. Rainey, F. A. (ed.). Elsevier, p. 757-782 26 p. (Methods in Microbiology; vol. 35).

Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

Open Access

Triterpenoids, including one with smooth muscle relaxant activity, from Rubus idaeus (Raspberry) leaves

Rojas-Vera, J., Dacke, C. G., Patel, A. V. & Blunden, G., 2006, In: Natural Product Communications. 1, p. 613-617 5 p.

Research output: Contribution to journal › Article › peer-review

2005

Anaerobic ammonia-oxidizing bacteria and related activity in Baltimore Inner Harbor sediment

Tal, Y., Watts, J. & Schreier, H., 2005, In: Applied and Environmental Microbiology. 71, 4, p. 1816-1821 6 p.

Research output: Contribution to journal › Article › peer-review

A PCR-based specific assay reveals a population of bacteria within the Chloroflexi associated with the reductive dehalogenation of polychlorinated biphenyls

Watts, J., Fagervold, S., May, H. & Sowers, K., 2005, In: Microbiology. 151, 6, p. 2039-2046 8 p.

Research output: Contribution to journal › Article › peer-review

A questionnaire survey to establish the perceptions of UK specifiers concerning the key material attributes of timber for USE in marine and fresh water engineering

Williams, J. R., Sawyer, G. S., Cragg, S. M. & Simm, J., 1 Jan 2005, In: Journal of the Institute of Wood Science. 17, 1, p. 41-50 10 p.

Research output: Contribution to journal › Article › peer-review

Catalytic mechanism of C–C hydrolase MhpC from Escherichia coli: kinetic analysis of His263 and Ser110 site-directed mutants

Li, C., Montgomery, M. G., Mohammed, F., Li, J-J., Wood, S. P. & Bugg, T. D. H., 1 Feb 2005, In: Journal of Molecular Biology. 346, 1, p. 241-251

Research output: Contribution to journal › Article › peer-review

Open Access

Course-related extra curricular activities of M. Pharm undergraduatestudents at the University of Portsmouth

Brown, D., Patel, A. V., Soobiah, T., Mohammed, A., Ahmed, M. & Hussain, S., 2005, In: Pharmacy Education. 5, p. 143-156 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Deuterium NMR Studies of Framework and Guest Mobility in the metal-organic framework compound MOF-5, Zn₄O(O₂CC₆H₄CO₂)₃

Gonzalez, J., Devi, R. N., Tunstall, D. P., Cox, P. & Wright, P. A., 15 Sept 2005, In: Microporous and Mesoporous Materials. 84, 1-3, p. 97–104

Research output: Contribution to journal › Article › peer-review

Open Access

Development of an assay for the quantification of type I collagen synthesis in the guinea pig

Quasnichka, H. L., Tarlton, J. F., Anderson-MacKenzie, J. M., Billingham, M. E. J., Bailey, A. J. & Pickford, A. R., Feb 2005, In: Journal of Immunological Methods. 297, 1-2, p. 133-141 9 p.

Research output: Contribution to journal › Article › peer-review

Gelatin binding to the 6F11F22F2 fragment of fibronectin is independent of module−module interactions

Pagett, A., Campbell, I. & Pickford, A., 2005, In: Biochemistry. 44, 44, p. 14682-14687 6 p.

Research output: Contribution to journal › Article › peer-review

Gelatin binding to the 8F19F1 module pair of human fibronectin requires site-specific N-glycosylation

Millard, C. J., Campbell, I. D. & Pickford, A. R., 15 Aug 2005, In: FEBS Letters. 579, 20, p. 4529-4534 6 p.

Research output: Contribution to journal › Article › peer-review

ICI182,780 induces p21Waf1 gene transcription through releasing histone deacetylase 1 and estrogen receptor alpha from Sp1 sites to induce cell cycle arrest in MCF-7 breast cancer cell line

Varshochi, R., Halim, F., Sunters, A., Alao, J. P., Madureira, P. A., Hart, S. M., Ali, S., Vigushin, D. M., Coombes, R. C. & Lam, E. W-F., 4 Feb 2005, In: The Journal of Biological Chemistry. 280, 5, p. 3185-3196 12 p.

Research output: Contribution to journal › Article › peer-review

Motion of aromatic hydrocarbons in the microporous aluminum methylphosphonates AlMePO-α and AlMePO-β

Gonzalez, J., Devi, R., Wright, P., Tunstall, D. & Cox, P., 2005, In: The Journal of Physical Chemistry B. 109, 46, p. 21700-21709 10 p.

Research output: Contribution to journal › Article › peer-review

Mucoadhesive, triclosan-loaded polymer microspheres for application to the oral cavity: Preparation and controlled release characteristics

Kockisch, S., Rees, G. D., Tsibouklis, J. & Smart, J. D., 1 Jan 2005, In: European Journal of Pharmaceutics and Biopharmaceutics. 59, 1, p. 207-216 10 p.

Research output: Contribution to journal › Article › peer-review

Murine gamma-herpesvirus 68 latency protein M2 binds to Vav signaling proteins and inhibits B-cell receptor-induced cell cycle arrest and apoptosis in WEHI-231 B cells

Madureira, P. A., Matos, P., Soeiro, I., Dixon, L. K., Simas, J. P. & Lam, E. W-F., 11 Nov 2005, In: The Journal of Biological Chemistry. 280, 45, p. 37310-37318 9 p.

Research output: Contribution to journal › Article › peer-review

Non-toxic coatings that inhibit bacterial adhesion

Barbu, E., Nevell, T. G. & Tsibouklis, J., 2005, In: Pharmaceutical Manufacturing and Packing Sourcer. p. 84-90

Research output: Contribution to journal › Article › peer-review

Phosphatidylinositol 3-kinase is required for the transcriptional activation of cyclin D2 in BCR activated primary mouse B lymphocytes

Glassford, J., Vigorito, E., Soeiro, I., Madureira, P. A., Zoumpoulidou, G., Brosens, J. J., Turner, M. & Lam, E. W-F., 6 Sept 2005, In: European Journal of Immunology. 35, 9, p. 2748-2761 14 p.

Research output: Contribution to journal › Article › peer-review

Preliminary study of the commercial potential of oyster beds at Emsworth

Pattisson, N., Wattage, P., Cragg, S., Stanton, S., Dossor, P., Strevens, C., Banks, G., Capon, N. & Jones, A., Sept 2005, Portsmouth: University of Portsmouth, 64 p.

Research output: Working paper

Sequential reductive dechlorination of meta-chlorinated polychlorinated biphenyl congeners in sediment microcosms by two different Chloroflexi phylotypes

Fagervold, S., Watts, J., May, H. & Sowers, K., 2005, In: Applied and Environmental Microbiology. 71, 12, p. 8085-8090 6 p.

Research output: Contribution to journal › Article › peer-review

Stabilization of chromium by reductase enzyme treatment

Rahman, K. S. M. & Murthy, M. A. V., 1 Dec 2005, Stabilisation/Solidification Treatment and Remediation: Advances in S/S for Waste and Contaminated Land - Proceedings of the Int. Conf. on Stabilisation/Solidification Treatment and Remediation. p. 347-356 10 p.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Structure of Escherichia coli RNase E catalytic domain and implications for RNA turnover

Callaghan, A., Marcaida, M., Stead, J., McDowall, K., Scott, W. & Luisi, B., 2005, In: Nature. 437, 7062, p. 1187-1191 5 p.

Research output: Contribution to journal › Article › peer-review

The hydrothermal synthesis of zeolites: precursors, intermediates and reaction mechanism

Cundy, C. & Cox, P., 5 Jul 2005, In: Microporous and Mesoporous Materials. 82, 1-2, p. 1-78 78 p.

Research output: Contribution to journal › Article › peer-review

The serotonin transporter (SLC6A4) is present in B-cell clones of diverse malignant origin: probing a potential antitumor target for psychotropics

Meredith, E. J., Holder, M. J., Chamba, A., Challa, A., Drake-Lee, A., Bunce, C. M., Drayson, M. T., Pilkington, G., Blakely, R. D., Dyer, M. J. S., Barnes, N. M. & Gordon, J., May 2005, In: FASEB Journal. 19, 7, p. 1187-

Research output: Contribution to journal › Article › peer-review

The structure of the C–C bond hydrolase MhpC provides insights into its catalytic mechanism

Dunn, G., Montgomery, M. G., Mohammed, F., Coker, A., Cooper, J. B., Robertson, T., Garcia, J-L., Bugg, T. D. H. & Wood, S. P., 1 Feb 2005, In: Journal of Molecular Biology. 346, 1, p. 253-265

Research output: Contribution to journal › Article › peer-review

Open Access

Vinylpyrrolidone-co-(meth)acrylic acid inserts for ocular drug delivery: synthesis and evaluation

Barbu, E., Sarvaiya, I., Green, K. L., Nevell, T. G. & Tsibouklis, J., 15 Sept 2005, In: Journal of Biomedical Materials Research Part A. 74A, 4, p. 598-606

Research output: Contribution to journal › Article › peer-review

Zeolite synthesis using flexible diquaternary alkylammonium ions (CnH2n+1)2HN+(CH2)5N+H(CnH2n+1)2 with n = 1−5 as structure-directing agents

Han, B., Lee, S-H., Shin, C-H., Cox, P. & Hong, S., 2005, In: Chemistry of Materials. 17, 3, p. 477-486 10 p.

Research output: Contribution to journal › Article › peer-review

Zygotic nucleosome assembly protein–like 1 has a specific, non–cell autonomous role in hematopoiesis

Abu-Daya, A., Steer, W., Trollope, A., Friedeberg, C., Patient, R., Thorne, A. & Guille, M., 15 Jul 2005, In: Blood. 106, 2, p. 514-520 7 p.

Research output: Contribution to journal › Article › peer-review

“Zn-Link”: a metal-sharing interface that organizes the quaternary structure and catalytic site of the endoribonuclease, RNase E

Callaghan, A., Redko, Y., Murphy, L., Grossmann, J., Yates, D., Garman, E., Ilag, L., Robinson, C. V., Symmons, M., McDowall, K. & Luisi, B., 2005, In: Biochemistry. 44, 12, p. 4667-4675 9 p.

Research output: Contribution to journal › Article › peer-review

2004

Application of a micro-respirometric volumetric method to respiratory measurements of larvae of the Pacific oyster Crassostrea gigas

Goulletquer, P., Wolowicz, M., Latala, A., Brown, C. & Cragg, S., 2004, In: Aquatic Living Resources. 17, 2, p. 195-200 6 p.

Research output: Contribution to journal › Article › peer-review

Bioremediation of hydrocarbon contaminated gasoline station soil by a bacterial consortium

Rahman, K. S. M., Street, G., Lord, R., Kane, G. & Banat, I. M., 11 Oct 2004, WIT Transactions on Ecology and the Environment. Vol. 10. p. 401-407 7 p. (Environmental Studies).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Crystallization and X-ray analysis of the Y75N mutant of Mucor pusillus pepsin complexed with inhibitor

Badasso, M. O., Dhanaraj, V., Wood, S. P., Cooper, J. B. & Blundell, T. L., 1 Apr 2004, In: Acta Crystallographica Section D Biological Crystallography. 60, 4, p. 770-772

Research output: Contribution to journal › Article › peer-review

Open Access

Development of two PCR-based techniques for detecting helical and coccoid forms of Helicobacter pylori

Shahamat, M., Alavi, M., Watts, J., Gonzalez, J., Sowers, K., Maeder, D. & Robb, F., 2004, In: Journal of Clinical Microbiology. 42, 8, p. 3613-3619 7 p.

Research output: Contribution to journal › Article › peer-review

Dual-stimuli-responsive hydrogels based on poly(N-isopropylacrylamide)/chitosan semi-interpenetrating networks

Verestiuc, L., Ivanov, C., Barbu, E. & Tsibouklis, J., 9 Jan 2004, In: International Journal of Pharmaceutics. 269, 1, p. 185-194

Research output: Contribution to journal › Article › peer-review

Effect of treatment with dornase alpha on airway inflammation in patients with cystic fibrosis

Paul, K., Rietschel, E., Ballmann, M., Griese, M., Worlitzsch, D., Shute, J., Chen, C., Schink, T., Doring, G., Van Koningsbruggen, S., Wahn, U. & Ratjen, F., 15 Mar 2004, In: American Journal of Respiratory and Critical Care Medicine. 169, 6, p. 719-725

Research output: Contribution to journal › Article › peer-review

High affinity streptococcal binding to human fibronectin requires specific recognition of sequential F1 modules

Schwarz-Linek, U., Pilka, E., Pickford, A., Kim, J. H., Hook, M., Campbell, I. & Potts, J., 2004, In: The Journal of Biological Chemistry. 279, 37, p. 39017-39025 9 p.

Research output: Contribution to journal › Article › peer-review

In situ evaluation of drug-loaded microspheres on a mucosal surface under dynamic test conditions

Kockisch, S., Rees, G. D., Young, S. A., Tsibouklis, J. & Smart, J. D., 19 May 2004, In: International Journal of Pharmaceutics. 276, 1-2, p. 51-58 8 p.

Research output: Contribution to journal › Article › peer-review

Intact RNA-binding domains are necessary for structure-specific DNA binding and transcription control by CBTF122 during Xenopus development

Scarlett, G., Elgar, S., Cary, P., Noble, A., Oxford, R., Kneale, G. & Guille, M., Dec 2004, In: The Journal of Biological Chemistry. 279, 50, p. 52447-52455 9 p.

Research output: Contribution to journal › Article › peer-review

Isotopic labeling of recombinant proteins from the methylotrophic yeast Pichia pastoris

Pickford, A. & O'Leary, J., 2004, Protein NMR techniques. Downing, A. (ed.). 278 ed. Totowa: Humana Press, p. 17-33 17 p. (Methods in molecular biology; no. 278).

Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

Open Access

Linker length modulates DNA cross-linking reactivity and cytotoxic potency of C8/C8‘ ether-linked C2-exo-unsaturated pyrrolo[2,1-c][1,4]benzodiazepine (PBD) dimers

Gregson, S., Howard, P. W., Gullick, D., Hamaguchi, A., Corcoran, K., Brooks, N. A., Hartley, J., Jenkins, T., Patel, S., Guille, M. & Thurston, D., 26 Feb 2004, In: Journal of Medicinal Chemistry. 47, 5, p. 1161-1174 14 p.

Research output: Contribution to journal › Article › peer-review

Metamorphosis of a scleractinian coral in response to microbial biofilms

Webster, N., Smith, L., Heyward, A., Watts, J., Webb, R., Blackall, L. & Negri, A., 2004, In: Applied and Environmental Microbiology. 70, 2, p. 1213-1221 9 p.

Research output: Contribution to journal › Article › peer-review

Microbial anaerobic demethylation and dechlorination of chlorinated hydroquinone metabolites synthesized by Bbsidiomycete fungi

Milliken, C., Meier, G., Watts, J., Sowers, K. & May, H., 2004, In: Applied and Environmental Microbiology. 70, 1, p. 385-392 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Perspectives for drug intervention in amyloid diseases

Kolstoe, S. & Wood, S., Feb 2004, In: Current Drug Targets. 5, 2, p. 151-158 8 p.

Research output: Contribution to journal › Article › peer-review

Institute of Life Sciences and Healthcare

Research output

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