Research outputs per year
Research outputs per year
- 39 results
Search results
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2024
A high-throughput screening platform for engineering poly(ethylene terephthalate) hydrolases
Groseclose, T., Kober, E., Clark, M. A., Moore, B. R., Banerjee, S., Bemmer, V. L., Beckham, G. T., Pickford, A., Dale, T. & Nguyen, H., 17 Sept 2024, In: ACS Catalysis. 14, p. 14622−14638 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Downloads (Pure) -
2023
Biochemical and structural characterization of a Sphingomonas diarylpropane lyase for cofactorless deformylation
Kuatsjah, E., Zahn, M., Chen, X., Kato, R., Hinchen, D. J., Konev, M., Katahira, R., Orr, C., Wagner, A., Zou, Y., Haugen, S. J., Ramirez, K., Michener, J. K., Pickford, A., Kamimura, N., Masai, E., Houk, K. N., McGeehan, J. & Beckham, G. T., 18 Jan 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 4, 9 p., e2212246120.Research output: Contribution to journal › Article › peer-review
Open AccessFile50 Downloads (Pure) -
Concentration-dependent inhibition of mesophilic PETases on poly(ethylene terephthalate) can be eliminated by enzyme engineering
Avilan, L., Lichtenstein, B., Koenig, G., Zahn, M., Allen, M. D., Oliveira Pessoa, L., Clark, M. A., Bemmer, V. L., Graham, R., Austin, H. P., Dominick, G., Johnson, C. W., Beckham, G. T., McGeehan, J. & Pickford, A., 21 Apr 2023, In: ChemSusChem. 16, 8, 12 p., e202202277.Research output: Contribution to journal › Article › peer-review
Open AccessFile48 Downloads (Pure) -
Initiation of fatty acid biosynthesis in Pseudomonas putida KT2440
McNaught, K., Kuatsjah, E., Zahn, M., Prates, E., Shao, H., Bentley, G., Pickford, A., Gruber, J., Hestmark, K., Jacobson, D., Poirier, B., Ling, C., San Marchi, M., Michener, W. E., Nicora, C., Sanders, J., Szostkiewicz, C. J., Veličković, D., Zhou, M., Munoz, N., & 7 others, 1 Mar 2023, In: Metabolic Engineering. 76, p. 193-203Research output: Contribution to journal › Article › peer-review
Open AccessFile58 Downloads (Pure) -
2022
Comparative performance of PETase as a function of reaction conditions, substrate properties, and product accumulation
Erickson, E., Shakespeare, T. J., Bratti, F., Buss, B., Graham, R., Hawkins, M., Koenig, G., Michener, W. E., Miscall, J., Ramirez, K., Rorrer, N. A., Zahn, M., Pickford, A., McGeehan, J. & Beckham, G. T., 10 Jan 2022, In: ChemSusChem. 15, 1, 11 p., e202101932.Research output: Contribution to journal › Article › peer-review
Open AccessFile109 Downloads (Pure) -
Particle size reduction of poly(ethylene terephthalate) increases the rate of enzymatic depolymerization but does not increase overall conversion extent
Brizendine, R. K., Erickson, E., Haugen, S. J., Ramirez, K., Miscall, J., Salvachúa, D., Pickford, A., Sobkowicz, M. J., McGeehan, J. & Beckham, G. T., 18 Jul 2022, In: ACS Sustainable Chemistry and Engineering. 10, p. 9131–9140Research output: Contribution to journal › Article › peer-review
Open AccessFile144 Downloads (Pure) -
Sourcing thermotolerant poly(ethylene terephthalate) hydrolase scaffolds from natural diversity
Erickson, E., Gado, J. E., Avilan, L., Bratti, F., Brizendine, R. K., Cox, P., Gill, R., Graham, R., Kim, D-J., Koenig, G., Michener, W. E., Poudel, S., Ramirez, K. J., Shakespeare, T. J., Zahn, M., Boyd, E. S., Payne, C., DuBois, J. L., Pickford, A. R., Beckham, G. T., & 1 others, 21 Dec 2022, In: Nature Communications. 13, 1, 15 p., 7850.Research output: Contribution to journal › Article › peer-review
Open AccessFile80 Downloads (Pure) -
The role of binding modules in enzymatic poly(ethylene terephthalate) hydrolysis at high solids loadings
Graham, R., Erickson, E., Brizendine, R. K., Salvachúa, D., Michener, W. E., Li, Y., Tan, Z., Beckham, G. T., McGeehan, J. & Pickford, A., 20 Oct 2022, In: Chem Catalysis. 2, 10, p. 2644-2657Research output: Contribution to journal › Article › peer-review
Open AccessFile51 Downloads (Pure) -
2021
Techno-economic, life cycle, and socio-economic impact analysis of enzymatic recycling of poly(ethylene terephthalate)
Singh, A., Rorrer, N. A., Nicholson, S., Erickson, E., DesVeaux, J., Avelino, A., Lamers, P., Bhatt, A., Zhang, Y., Avery, G., Tao, L., Pickford, A., Carpenter, A., McGeehan, J. & Beckham, G. T., 15 Sept 2021, In: Joule. 5, p. 1-25 25 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile352 Downloads (Pure) -
2019
Application of mRNA arrays for the production of mCherry reporter-protein arrays for quantitative gene expression analysis
Norouzi, M., Pickford, A., Butt, L., Vincent, H. & Callaghan, A., 25 Jan 2019, (Early online) In: ACS Synthetic Biology.Research output: Contribution to journal › Article › peer-review
Open AccessFile316 Downloads (Pure) -
Collagenolytic matrix metalloproteinases antagonize proteinase-activated receptor-2 activation, providing insights into extracellular matrix turnover
Falconer, A. M. D., Chan, C. M., Gray, J., Nagashima, I., Holland, R. A., Shimizu, H., Pickford, A. R., Rowan, A. D. & Wilkinson, D. J., 19 May 2019, (Early online) In: Journal of Biological Chemistry. 294, 26, p. 10266-10277Research output: Contribution to journal › Article › peer-review
Open AccessFile220 Downloads (Pure) -
Tuning the matrix metalloproteinase-1 degradability of peptide amphiphile nanofibers through supramolecular engineering
Shi, Y., Ferreira, D., Banerjee, J., Pickford, A. & Azevedo, H. S., 1 Dec 2019, In: Biomaterials Science. 7, 12, p. 5132-5142Research output: Contribution to journal › Article › peer-review
Open AccessFile113 Downloads (Pure) -
2018
Current insights into Matrix metalloproteinases and glioma progression: transcending the degradation boundary
Pullen, N., Pickford, A., Perry, M. M., Jaworski, D. M., Loveson, K., Arthur, D., Holliday, J., Van Meter, T., Peckham, R., Younas, W., Briggs, S., MacDonald, S., Butterfield, T., Constantinou, M. & Fillmore, H., 17 Sept 2018, In: Metalloproteinases in Medicine. 5, p. 13-30Research output: Contribution to journal › Article › peer-review
Open AccessFile936 Downloads (Pure) -
High-density functional-RNA arrays as a versatile platform for studying RNA-based interactions
Phillips, J., Butt, L., Henderson, C., Devonshire, M. A., Healy, J., Conway, S. J., Locker, N., Pickford, A., Vincent, H. & Callaghan, A., 21 Aug 2018, In: Nucleic Acids Research. 46, 14, 10 p., e86.Research output: Contribution to journal › Article › peer-review
Open AccessFile756 Downloads (Pure) -
2017
Inhibition of homologous phosphorolytic ribonucleases by citrate may represent an evolutionarily conserved communicative link between RNA degradation and central metabolism
Stone, C., Butt, L., Bufton, J., Lourenco, D. C., Gowers, D., Pickford, A., Cox, P., Vincent, H. & Callaghan, A., 5 May 2017, In: Nucleic Acids Research. 45, 8, p. 4655-4666Research output: Contribution to journal › Article › peer-review
Open AccessFile185 Downloads (Pure) -
2013
An improved method for surface immobilisation of RNA: application to small Non-Coding RNA - mRNA pairing
Vincent, H., Phillips, J., Henderson, C., Roberts, A. J., Stone, C., Mardle, C., Butt, L., Gowers, D., Pickford, A. & Callaghan, A., 14 Nov 2013, In: PLoS One. 8, 11, p. e79142Research output: Contribution to journal › Article › peer-review
Open AccessFile154 Downloads (Pure) -
2011
Design and structure of stapled peptides binding to estrogen receptors
Phillips, C., Roberts, L. R., Schade, M., Bazin, R., Bent, A., Davies, N. L., Moore, R., Pannifer, A. D., Pickford, A. R., Prior, S. H., Read, C. M., Scott, A., Brown, D. G., Xu, B. & Irving, S. L., 29 Jun 2011, In: Journal of the American Chemical Society. 133, 25, p. 9696-9699Research output: Contribution to journal › Article › peer-review
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The interface between catalytic and hemopexin domains in matrix metalloproteinase-1 (MMP-1) conceals a collagen binding exosite
Arnold, L., Butt, L., Prior, S., Read, C., Fields, G. & Pickford, A., 30 Dec 2011, In: The Journal of Biological Chemistry. 286, p. 45073-45082 10 p.Research output: Contribution to journal › Article › peer-review
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2010
Implications for collagen binding from the crystallographic structure of fibronectin 6FnI1-2FnII7FnI
Erat, M., Schwarz-Linek, U., Pickford, A., Farndale, R., Campbell, I. & Vakonakis, I., 29 Oct 2010, In: The Journal of Biological Chemistry. 285, 44, p. 33764-33770 7 p.Research output: Contribution to journal › Article › peer-review
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2007
Structural basis of integrin activation by talin
Wegener, K., Partridge, A., Han, J., Pickford, A., Liddington, R., Ginsberg, M. & Campbell, I., 12 Jan 2007, In: Cell. 128, 1, p. 171-182 12 p.Research output: Contribution to journal › Article › peer-review
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The role of the fibronectin IGD motif in stimulating fibroblast migration
Millard, C., Ellis, I., Pickford, A., Schor, A., Schor, S. & Campbell, I., 2007, In: The Journal of Biological Chemistry. 282, 49, p. 35530-35535 6 p.Research output: Contribution to journal › Article › peer-review
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2006
Structural insight into binding of Staphylococcus aureus to human fibronectin
Pilka, E., Werner, J., Schwarz-Linek, U., Pickford, A., Meenan, N., Campbell, I. & Potts, J., 2006, In: FEBS Letters. 580, 1, p. 273-277 5 p.Research output: Contribution to journal › Article › peer-review
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2005
Development of an assay for the quantification of type I collagen synthesis in the guinea pig
Quasnichka, H. L., Tarlton, J. F., Anderson-MacKenzie, J. M., Billingham, M. E. J., Bailey, A. J. & Pickford, A. R., Feb 2005, In: Journal of Immunological Methods. 297, 1-2, p. 133-141 9 p.Research output: Contribution to journal › Article › peer-review
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Gelatin binding to the 6F11F22F2 fragment of fibronectin is independent of module−module interactions
Pagett, A., Campbell, I. & Pickford, A., 2005, In: Biochemistry. 44, 44, p. 14682-14687 6 p.Research output: Contribution to journal › Article › peer-review
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Gelatin binding to the 8F19F1 module pair of human fibronectin requires site-specific N-glycosylation
Millard, C. J., Campbell, I. D. & Pickford, A. R., 15 Aug 2005, In: FEBS Letters. 579, 20, p. 4529-4534 6 p.Research output: Contribution to journal › Article › peer-review
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2004
High affinity streptococcal binding to human fibronectin requires specific recognition of sequential F1 modules
Schwarz-Linek, U., Pilka, E., Pickford, A., Kim, J. H., Hook, M., Campbell, I. & Potts, J., 2004, In: The Journal of Biological Chemistry. 279, 37, p. 39017-39025 9 p.Research output: Contribution to journal › Article › peer-review
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NMR studies of modular protein structures and their interactions
Pickford, A. & Campbell, I., 2004, In: Chemical Reviews. 104, 8, p. 3557-3566 10 p.Research output: Contribution to journal › Article › peer-review
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Structure of the regulatory hyaluronan binding domain in the inflammatory leukocyte homing receptor CD44
Teriete, P., Banerji, S., Noble, M., Blundell, C. D., Wright, A. J., Pickford, A., Lowe, E., Mahoney, D. J., Tammi, M. I., Kahmann, J. D., Campbell, I. D., Day, A. J. & Jackson, D. G., 2004, In: Molecular Cell. 13, 4, p. 483-496 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile287 Downloads (Pure) -
2003
Pathogenic bacteria attach to human fibronectin through a tandem -zipper
Schwarz-Linek, U., Werner, J., Pickford, A., Gurusiddappa, S., Kim, J. H., Pilka, E., Briggs, J. A. G., Gough, T., Hook, M., Campbell, I. & Potts, J., 2003, In: Nature. 423, 6936, p. 177-181 5 p.Research output: Contribution to journal › Article › peer-review
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The Link module from ovulation- and inflammation-associated protein TSG-6 changes conformation on hyaluronan binding
Blundell, C., Mahoney, D., Almond, A., DeAngelis, P., Kahmann, J., Teriete, P., Pickford, A., Campbell, I. & Day, A., 2003, In: The Journal of Biological Chemistry. 278, 49, p. 49261-49270 10 p.Research output: Contribution to journal › Article › peer-review
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2001
Binding of a peptide from a Streptococcus dysgalactiae MSCRAMM to the N-terminal F1 module pair of human fibronectin involves both modules
Schwarz-Linek, U., Plevin, M. J., Pickford, A. R., Höök, M., Campbell, I. D. & Potts, J. R., 25 May 2001, In: FEBS Letters. 497, 2-3, p. 137-140 4 p.Research output: Contribution to journal › Article › peer-review
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The hairpin structure of the 6F11F22F2 fragment from human fibronectin enhances gelatin binding
Pickford, A., Smith, S., Staunton, D., Boyd, J. & Campbell, I., 2001, In: EMBO Journal. 20, 7, p. 1519-1529 11 p.Research output: Contribution to journal › Article › peer-review
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2000
Identification of residues involved in the interaction of Staphylococcus aureus fibronectin-binding protein with the 4F15F1 module pair of human fibronectin using heteronuclear NMR spectroscopy
Penkett, C. J., Dobson, C. M., Smith, L. J., Bright, J. R., Pickford, A. R., Campbell, I. D. & Potts, J. R., 21 Mar 2000, In: Biochemistry. 39, 11, p. 2887-2893 7 p.Research output: Contribution to journal › Article › peer-review
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Interface characterization of the type II module pair from fibronectin
Smith, S. P., Hashimoto, Y., Pickford, A. R., Campbell, I. D. & Werner, J. M., 25 Jul 2000, In: Biochemistry. 39, 29, p. 8374-8381 8 p.Research output: Contribution to journal › Article › peer-review
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The relative orientation of the fibronectin 6F11F2 module pair: A 15N NMR relaxation study
Hashimoto, Y., Smith, S. P., Pickford, A. R., Bocquier, A. A., Campbell, I. D. & Werner, J. M., 2000, In: Journal of Biomolecular Screening. 17, 3, p. 203-214 12 p.Research output: Contribution to journal › Article › peer-review
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1999
Solution structure of a pair of modules from the gelatin-binding domain of fibronectin
Bocquier, A. A., Potts, J. R., Pickford, A. R. & Campbell, I. D., 15 Dec 1999, In: Structure. 7, 12, p. 1451-1460 10 p.Research output: Contribution to journal › Article › peer-review
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Solution structure of the N-terminal F1 module pair from human fibronectin
Potts, J. R., Bright, J. R., Bolton, D., Pickford, A. R. & Campbell, I. D., 29 Jun 1999, In: Biochemistry. 38, 26, p. 8304-8312 9 p.Research output: Contribution to journal › Article › peer-review
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1998
Solution structure of the glycosylated second type 2 module of fibronectin
Sticht, H., Pickford, A. R., Potts, J. R. & Campbell, I. D., 13 Feb 1998, In: Journal of Molecular Biology. 276, 1, p. 177-187 11 p.Research output: Contribution to journal › Article › peer-review
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1997
Solution structure of a type 2 module from fibronectin: Implications for the structure and function of the gelatin-binding domain
Pickford, A. R., Potts, J. R., Bright, J. R., Phan, I. & Campbell, I. D., 15 Mar 1997, In: Structure. 5, 3, p. 359-370 12 p.Research output: Contribution to journal › Article › peer-review