'Condition specific engineering of P. putida for rhamnolipid production'
This project focuses on the growing demand for rhamnolipids production owing to its wide range of industrial and biomedical applications, including pharmaceuticals, cosmetics and detergents. These amphiphilic molecules are produced on the surfaces of or excreted extracellularly by bacteria including Pseudomonas aeruginosa. However, Pseudomonas putida is a model organism with greater metabolic versatility and potential for industrial applications. Exploring and characterising computationally the metabolism of P. putida at genome-scale and in a condition-specific fashion we can elucidate optimal growth medium and metabolic interventions to optimise the utilisation of aromatic carbon sources for bioremediation and biotechnological purposes.
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