Darek Gorecki

Search results

• 2024

  Differential expression of DMD transcripts as a novel prognostic biomarker in histologically diverse mesotheliomas

  Alnassar, N., Derry, J. M. J., Banna, G. L. & Gorecki, D. C., 29 Apr 2024, In: Translational Lung Cancer Research. 13, 4, p. 733-748

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  11 Downloads (Pure)

• Investigating the involvement of C−X−C Motif Chemokine 5 and P2X7 purinoceptor in ectopic calcification in mouse models of Duchenne muscular dystrophy

  Rumney, R. M. H., Pomeroy, J. & Górecki, D. C., 25 Jun 2024, (Early online) In: Journal of Cellular Biochemistry. 11 p., e30617.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  9 Downloads (Pure)

• The P2×7 receptor is a master regulator of microparticle and mitochondria exchange in mouse microglia

  Falzoni, S., Vultaggio-Poma, V., Chiozzi, P., Tarantini, M., Adinolfi, E., Boldrini, P., Giuliani, A. L., Morciano, G., Tang, Y., Gorecki, D. & Di Virgilio, F., 17 Apr 2024, (Early online) In: Function.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  20 Downloads (Pure)
• 2023

  Automated multi-sample DNA extraction for genotyping live Xenopus embryos

  Alles, N., Guille, M. & Górecki, D. C., 1 Mar 2023, In: Developmental Dynamics. 252, 3, p. 429-438 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  66 Downloads (Pure)

• Downregulation of dystrophin expression occurs across diverse tumors, correlates with the age of onset, staging and reduced survival of patients

  Alnassar, N., Borczyk, M., Tsagkogeorga, G., Korostynski, M., Han, N. & Górecki, D. C., 21 Feb 2023, In: Cancers. 15, 5, 28 p., 1378.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  60 Downloads (Pure)

• Primary mouse myoblast metabotropic purinoceptor profiles and calcium signalling differ with their muscle origin and are altered in mdx dystrophinopathy

  Róg, J., Oksiejuk, A., Górecki, D. C. & Zabłocki, K., 1 Dec 2023, In: Scientific Reports. 13, 1, 18 p., 9333.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  41 Downloads (Pure)

• The P2X7 purinoceptor in pathogenesis and treatment of dystrophino- and sarcoglycanopathies

  Gόrecki, D. C. & Rumney, R. M. H., 1 Apr 2023, In: Current Opinion in Pharmacology. 69, 8 p., 102357.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  50 Downloads (Pure)

• The role of P2X7 purinoceptors in the pathogenesis and treatment of muscular dystrophies

  Zabłocki, K. & Górecki, D. C., 29 May 2023, In: International Journal of Molecular Sciences. 24, 11, 15 p., 9434.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  52 Downloads (Pure)
• 2022

  Biomimetic generation of the strongest known biomaterial found in limpet tooth

  Rumney, R. M. H., Robson, S., Kao, A., Barbu, E., Bozycki, L., Smith, J., Cragg, S., Couceiro, F., Parwani, R. N., Tozzi, G., Stuer, M., Barber, A. H., Ford, A. & Gorecki, D., 7 Jul 2022, In: Nature Communications. 13, 13 p., 3753.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • teeth 100%
  • chitin 66%
  • biomimetics 66%
  • Chitin 66%
  • Cell 50%
  72 Downloads (Pure)

• Dystrophin immunogenicity and requirement in myogenic cells: Paradigm shift in gene therapy for DMD

  Górecki, D. C., 24 Nov 2022, In: Clinical and Translational Medicine. 12, 11, 3 p., e1122.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  File
  32 Downloads (Pure)

• Loss of full-length dystrophin expression results in major cell-autonomous abnormalities in proliferating myoblasts

  Gosselin, M. R. F., Mournetas, V., Borczyk, M., Verma, S., Occhipinti, A., Róg, J., Bozycki, L., Korostynski, M., Robson, S. C., Angione, C., Pinset, C. & Gorecki, D. C., 27 Sept 2022, In: eLife. 11, 43 p., e75521.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  43 Downloads (Pure)

• P2X7 Purinoceptor Affects Ectopic Calcification of Dystrophic Muscles

  Rumney, R. M. H., Róg, J., Chira, N., Kao, A. P., Al-Khalidi, R. & Górecki, D. C., 14 Jul 2022, In: Frontiers in Pharmacology. 13, 12 p., 935804.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • muscles 100%
  • Phosphate 87%
  • phosphates 87%
  • Mineralization 50%
  • Macrophage 50%
  79 Downloads (Pure)

• Specific dystrophins selectively associate with inhibitory and excitatory synapses of the mouse cerebellum and their loss alters expression of P2X7 purinoceptors and pro-inflammatory mediators

  Jackson, T., Seifi, M., Górecki, D. C. & Swinny, J. D., 1 Oct 2022, In: Cellular and Molecular Neurobiology. 42, p. 2357-2377 21 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Dystrophin 100%
  • Muscular Dystrophy 77%
  • genes 55%
  • Synapse 44%
  • Gene Product 44%
  87 Downloads (Pure)

• α-Dystrobrevin knockout mice have increased motivation for appetitive reward and altered brain cannabinoid receptor 1 expression

  Hawkes, C. A., Heath, C. J., Sharp, M. M., Górecki, D. C. & Carare, R. O., 31 Aug 2022, In: Acta Neuropathologica Communications. 10, 1, 15 p., 127.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • receptors 100%
  • knock-out reactions 100%
  • proteins 85%
  • levels 71%
  • Motivation 71%
  28 Downloads (Pure)
• 2021

  Myogenesis modelled by human pluripotent stem cells: a multi‐omic study of Duchenne myopathy early onset

  Mournetas, V., Massouridès, E., Dupont, JB., Kornobis, E., Polvèche, H., Jarrige, M., Dorval, A. R. L., Gosselin, M. R. F., Manousopoulou, A., Garbis, S. D., Górecki, D. C. & Pinset, C., 17 Feb 2021, In: Journal of Cachexia, Sarcopenia and Muscle. 12, 1, p. 209-232 24 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Duchenne Muscular Dystrophy 100%
  • muscles 80%
  • Muscle Development 50%
  • humans 50%
  • Skeletal Muscle 50%
  124 Downloads (Pure)

• The α-dystrobrevins play a key role in maintaining the structure and function of the extracellular matrix–significance for protein elimination failure arteriopathies

  Sharp, M. M., Cassidy, J., Thornton, T., Lyles, J., Keable, A., Gatherer, M., Yasui, M., Abe, Y., Shibata, S., Weller, R. O., Górecki, D. C. & Carare, R. O., 1 Dec 2021, In: Acta Neuropathologica Communications. 9, 1, 15 p., 171.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Vascular Amyloidosis 100%
  • Cerebral Amyloid Angiopathy 100%
  • matrices 85%
  • Extracellular Matrix 85%
  • drainage 71%
  39 Downloads (Pure)
• 2020

  Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in human lung microvascular endothelial cells controls oxidative stress, reactive oxygen-mediated cell signaling and inflammatory responses

  Khalaf, M., Scott-Ward, T., Causer, A., Saynor, Z., Shepherd, A., Górecki, D., Lewis, A., Laight, D. & Shute, J., 29 Jul 2020, In: Frontiers in Physiology. 11, 20 p., 879.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • fibrosis 100%
  • Cystic Fibrosis Transmembrane Conductance Regulator 85%
  • Endothelial Cell 40%
  • humans 40%
  • Western Blot 40%
  153 Downloads (Pure)

• Engineering butylglyceryl-modified polysaccharides towards nanomedicines for brain drug delivery

  Bostanudin, M. F. B., Lalatsa, K., Gorecki, D. & Barbu, E., 15 May 2020, In: Carbohydrate Polymers. 236, 10 p., 116060.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • brain 100%
  • Pullulan 100%
  • comparative evaluations 66%
  • applications 66%
  • membranes 66%
  156 Downloads (Pure)

• Knockout and knock-in mouse models to study purinergic signaling

  Rumney, R. M. H. & Gorecki, D., Jan 2020, Purinergic Signalling: Methods and Protocols. Pelegrín, P. (ed.). Springer, p. 17-43 27 p. (Methods in Molecular Biology; vol. 2041).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

  Open Access

  • mice 100%
  • phenotype 60%
  • knock-out reactions 60%
  • Phenotype 60%
  • humans 40%

• Total absence of dystrophin expression exacerbates ectopic myofiber calcification and fibrosis and alters macrophage infiltration patterns

  Young, C., Gosselin, M. R. F., Rumney, R. M. H., Oksiejuk, A., Chira, N., Bozycki, L., Matryba, P., Łukasiewicz, K., Kao, A., Dunlop, J. N., Robson, S., Zabłocki, K. & Gorecki, D., 1 Jan 2020, In: American Journal of Pathology. 190, 1, p. 190-205 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Dystrophin 100%
  • muscles 66%
  • Phenotype 50%
  • Macrophage 50%
  • Calcification 50%
  145 Downloads (Pure)
• 2019

  Butylglyceryl pectin nanoparticles: synthesis, formulation and characterization

  Bostanudin, M. F., Arafat, M., Sarfraz, M., Górecki, D. C. & Barbu, E., 2 May 2019, In: Polymers. 11, 5, 12 p., 789.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • pectins 100%
  • Pectin 100%
  • stability 50%
  • nanoparticles 50%
  • Zeta Potential 50%
  117 Downloads (Pure)

• Dystrophic mdx mouse myoblasts exhibit elevated ATP/UTP-evoked metabotropic purinergic responses and alterations in calcium signalling

  Róg, J., Oksiejuk, A., Gosselin, M. R. F., Brutkowski, W., Dymkowska, D., Nowak, N., Robson, S., Górecki, D. C. & Zabłocki, K., 24 Jan 2019, (Early online) In: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • calcium 100%
  • muscles 57%
  • receptors 57%
  • myoblasts 57%
  • Duchenne Muscular Dystrophy 57%
  220 Downloads (Pure)

• P2X7 purinoceptor as a therapeutic target in muscular dystrophies

  Górecki, D. C., 1 Aug 2019, In: Current Opinion in Pharmacology. 47, p. 40-45 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • muscles 100%
  • atp 100%
  • Adenosine Triphosphate 100%
  • mutations 60%
  • Muscular Dystrophy 60%
  288 Downloads (Pure)
• 2018

  P2RX7 Purinoceptor as a therapeutic target - the second coming?

  Young, C. N. J. & Górecki, D. C., 28 Jun 2018, In: Frontiers in Chemistry. 6, 248.

  Research output: Contribution to journal › Literature review › peer-review

  Open Access

  File

  • P2RX7 100%
  • Antagonist 80%
  • Receptor 60%
  • receptors 60%
  • Development 40%
  248 Downloads (Pure)

• Proteomics analysis reveals a potential new target protein for lipid-lowering effect of Berberine8998

  Yu, C., Liu, G., Liu, X., Gui, Y., Liu, H., Zheng, H., Gorecki, D., Patel, A. V., Yu, C. & Wang, Y., 1 Sept 2018, In: Acta Pharmacologica Sinica. 39, p. 1473-1482 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Berberine 100%
  • fatty acids 71%
  • Fatty Acid 71%
  • cholesterol 57%
  • lipids 57%
  136 Downloads (Pure)

• Sustained activation of P2X7 induces MMP-2-evoked cleavage and functional purinoceptor inhibition

  Young, C. N. J., Chira, N., Róg, J., Al-Khalidi, R., Benard, M., Galas, L., Chan, P., Vaudry, D., Zabłocki, K. & Górecki, D. C., 1 Jun 2018, In: Journal of Molecular Cell Biology. 10, 3, p. 229-242 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • matrices 100%
  • Gelatinase A 100%
  • MMP2 100%
  • toxicity 75%
  • humans 50%
  200 Downloads (Pure)

• Zidovudine ameliorates pathology in the mouse model of Duchenne muscular dystrophy via P₂RX₇ purinoceptor antagonism

  Al-Khalidi, R., Panicucci, C., Cox, P., Chira, N., Róg, J., Young, C., Lloyd, R., Ambati, K., Ambati, J., Zabłocki, K., Gazzerro, E., Arkle, S., Bruno, C. & Gorecki, D., 11 Apr 2018, (Early online) In: Acta Neuropathologica Communications. 6, 17 p., 27.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • muscles 100%
  • Antagonist 66%
  • Duchenne Muscular Dystrophy 55%
  • P2RX7 55%
  • Muscle 55%
  141 Downloads (Pure)
• 2017

  Co-delivery of indoleamine 2,3-dioxygenase prevents loss of expression of an antigenic transgene in dystrophic mouse muscles

  Sharma, D., Al-khalidi, R., Edgar, S., An, Q., Wang, Y., Young, C., Nowis, D. & Gorecki, D. C., Feb 2017, In: Gene Therapy. 24, 2, p. 113-119

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • muscles 100%
  • Transgene 80%
  • Indoleamine 2,3 Dioxygenase 80%
  • Indoleamine 2,3-dioxygenase 80%
  • losses 60%
  237 Downloads (Pure)

• Investigations of octylglyceryl dextran-graft-poly(lactic acid) nanoparticles for peptide delivery to the brain

  Boussahel, A., Ibegbu, D. M., Lamtahri, R., Maucotel, J., Chuquet, J., Lefranc, B., Leprince, J., Roldo, M., Le Mével, J-C., Gorecki, D. & Barbu, E., 1 Apr 2017, In: Nanomedicine. 12, 8, p. 879-892 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • peptides 100%
  • Peptide 100%
  • nanoparticles 80%
  • delivery 60%
  • dextran 60%
  268 Downloads (Pure)
• 2016

  Dystrophin: the dead calm of a dogma

  Górecki, D. C., 18 Feb 2016, In: Rare Diseases. 4, 1, e1153777.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Duchenne Muscular Dystrophy 100%
  • Muscular Dystrophy 100%
  • muscles 85%
  • Dystrophin 71%
  • P2RX7 42%
  149 Downloads (Pure)

• Impact of P2RX7 ablation on the morphological, mechanical and tissue properties of bones in a murine model of duchenne muscular dystrophy

  Mohamad, N. S., Sinadinos, A., Gorecki, D., Zioupos, P. & Tong, J., 3 Oct 2016, In: Journal of Biomechanics. 49, 14, p. 3444-3451

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Bone 100%
  • bones 64%
  • P2RX7 47%
  • ablation 29%
  • Diseases 17%
  229 Downloads (Pure)
• 2015

  A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90

  Young, C., Sinadinos, A., Lefebvre, A., Chan, P., Arkle, S., Vaudry, D. & Gorecki, D., 20 Feb 2015, In: Autophagy. 11, 1, p. 113-130 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • P2RX7 100%
  • muscles 44%
  • atp 44%
  • apoptosis 33%
  • Autophagy 33%
  171 Downloads (Pure)

• Hollow-layered nanoparticles for therapeutic delivery of peptide prepared using electrospraying

  Rasekh, M., Young, C., Roldo, M., Lancien, F., Le Mével, J-C., Hafizi, S., Ahmad, Z., Barbu, E. & Gorecki, D., 1 Nov 2015, In: Journal of Materials Science: Materials in Medicine. 26, 11

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • particles 100%
  • peptides 100%
  • Peptide 100%
  • in vivo 75%
  • in vitro 50%
  306 Downloads (Pure)

• Nanoparticles of alkylglyceryl-dextran-graft-poly(lactic acid) for drug delivery to the brain: preparation and in vitro investigation

  Toman, P., Lien, C-F., Ahmad, Z., Dietrich, S., Smith, J. R., An, Q., Molnár, É., Pilkington, G. J., Górecki, D. C., Tsibouklis, J. & Barbu, E., 1 Sept 2015, In: Acta Biomaterialia. 23, 1, p. 250-262 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • nanoparticles 100%
  • dextran 85%
  • Dextran 85%
  • lactic acid 71%
  • Polylactic Acid 71%
  456 Downloads (Pure)

• P2RX7 purinoceptor: a therapeutic target for ameliorating the symptoms of Duchenne muscular dystrophy

  Sinadinos, A., Young, C. N. J., Al-Khalidi, R., Teti, A., Kalinski, P., Mohamad, S., Floriot, L., Henry, T., Tozzi, G., Jiang, T., Wurtz, O., Lefebvre, A., Shugay, M., Tong, J., Vaudry, D., Arkle, S., doRego, J-C. & Górecki, D. C., 13 Oct 2015, In: PLoS Medicine. 12, 10, 33 p., e1001888.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Duchenne Muscular Dystrophy 100%
  • muscles 91%
  • Muscular Dystrophy 91%
  • P2RX7 58%
  • Muscle 50%
  324 Downloads (Pure)

• Store-operated calcium entry contributes to abnormal Ca²⁺ signalling in dystrophic mdx mouse myoblasts

  Onopiuk, M., Brutkowski, W., Young, C., Krasowska, E., Rog, J., Ritso, M., Wojciechowska, S., Arkle, S., Zablocki, K. & Gorecki, D. C., 1 Mar 2015, In: Archives of Biochemistry and Biophysics. 569, p. 1-9

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • calcium 100%
  • myoblasts 57%
  • Store Operated Calcium Entry 57%
  • mutations 42%
  • Mutation 42%
  340 Downloads (Pure)
• 2014

  Aberrant location of inhibitory synaptic marker proteins in the hippocampus of dystrophin-deficient mice

  Krasowska, E., Zablocki, K., Gorecki, D. C. & Swinny, J. D., 2014, In: PLoS One. 9, 9, p. e108364 e108364.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Dystrophin 100%
  • Synapse 62%
  • Neurotransmission 50%
  • mice 50%
  • Hippocampus 37%
  182 Downloads (Pure)

• Receptory purynergiczne w prawidłowych i dystroficznych mięśniach szkieletowych

  Translated title of the contribution: Purinergic receptors in skeletal muscles in health and in muscular dystrophyKrasowska, E., Rog, J., Sinadinos, A., Young, C., Gorecki, D. & Zablocki, K., 2014, In: Postępy Biochemii. 60, 4, p. 483-489

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • receptors 100%
  • muscles 71%
  • Purinergic Receptor 28%
  • Purinergic P2 Receptor 28%
  • Muscle 28%
  166 Downloads (Pure)
• 2013

  CpG dinucleotide-specific hypermethylation of the TNS3 gene promoter in human renal cell carcinoma

  Carter, J., Gorecki, D., Mein, C., Ljungberg, B. & Hafizi, S., Jul 2013, In: Epigenetics. 8, 7, p. 739-747 9 p.

  Research output: Contribution to journal › Article › peer-review

  • kidneys 100%
  • genes 66%
  • promoters 66%
  • methylation 66%
  • carcinomas 66%
• 2012

  Absence of glial α-dystrobrevin causes abnormalities of the blood-brain barrier and progressive brain edema

  Lien, C-F., Mohanta, S., Frontczak-Baniewicz, M., Swinny, J., Zablocka, B. & Gorecki, D., 30 Nov 2012, In: The Journal of Biological Chemistry. 287, 49, p. 41374-41385 12 p.

  Research output: Contribution to journal › Article › peer-review

  • blood-brain barrier 100%
  • Blood Brain Barrier 100%
  • proteins 62%
  • brain 62%
  • Brain 62%

• Expression, assembly and function of novel C-terminal truncated variants of the mouse P2X7 receptor: Re-evaluation of P2X7 knockouts

  Masin, M., Young, C., Lim, K., Barnes, S. S., Xu, X. J., Marschall, V., Brutkowski, W., Mooney, E. R., Gorecki, D. & Murrell-Lagnado, R., Feb 2012, In: British Journal of Pharmacology. 165, 4, p. 978-993

  Research output: Contribution to journal › Article › peer-review

  • mice 100%
  • Reverse Transcription Polymerase Chain Reaction 85%
  • receptors 71%
  • Western Blot 71%
  • Knockout Mouse 57%

• In vitro assessment of alkylglyceryl-functionalized chitosan nanoparticles as permeating vectors for the blood–brain barrier

  Lien, C., Molnar, E., Toman, P., Tsibouklis, J., Pilkington, G., Gorecki, D. & Barbu, E., 9 Apr 2012, In: Biomacromolecules. 13, 4, p. 1067-1073 7 p.

  Research output: Contribution to journal › Article › peer-review

  • nanoparticles 100%
  • Nanoparticle 100%
  • blood-brain barrier 74%
  • Chitosan 74%
  • Blood Brain Barrier 74%

• Mechano-Growth Factor: an important cog or a loose screw in the repair machinery?

  Zabtocka, B., Goldspink, P., Goldspink, G. & Gorecki, D., Nov 2012, In: Frontiers in Experimental Endocrinology. 3, p. 131 1 p.

  Research output: Contribution to journal › Article › peer-review

  • tissues 100%
  • growth factors 100%
  • Tissues 100%
  • Growth Factors 66%
  • Growth Factor 66%

• P2X7 purinoceptor alterations in dystrophic mdx mouse muscles: relationship to pathology and potential target for treatment

  Young, C., Brutkowski, W., Lien, C., Arkle, S., Lochmuller, H., Zablocki, K. & Gorecki, D., May 2012, In: Journal of Cellular and Molecular Medicine. 16, 5, p. 1026-1037 12 p.

  Research output: Contribution to journal › Article › peer-review

  • muscles 100%
  • Purinergic P2X7 Receptor 62%
  • Muscle 50%
  • receptors 50%
  • Antagonist 50%

• Relationship between the affinity of PEO-PPO-PEO block copolymers for biological membranes and their cellular effects

  Redhead, M., Mantovani, G., Nawaz, S., Carbone, P., Gorecki, D., Alexander, C. & Bosquillon, C., 2012, In: Pharmaceutical Research. 29, 7, p. 1908-1918 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Poly(ethylene Glycol) 100%
  • membranes 85%
  • Polyphenylene Oxide 71%
  • copolymers 71%
  • Biological Product 71%

• Splice-variants of the P2X7 receptor reveal differential agonist-dependence and functional coupling with pannexin-1

  Xu, X. J., Boumechache, M., Robinson, L., Marschall, V., Gorecki, D., Masin, M. & Murrell-Lagnado, R., 15 Aug 2012, In: Journal of Cell Science. 125, 16, p. 3776-3789 14 p.

  Research output: Contribution to journal › Article › peer-review

  • receptors 100%
  • Eicosanoid Receptor 66%
  • Pannexin 41%
  • uptake 33%
  • nad 33%
• 2011

  Knockdown of MLC1 in primary astrocytes causes cell vacuolation: A MLC disease cell model

  Duarri, A., De Heredia, M., Capdevila-Nortes, X., Ridder, M., Montolio, M., Lopez-Hernandez, T., Boor, I., Lien, C., Hagemann, T., Messing, A. & Gorecki, D., Jul 2011, In: Neurobiology of Disease. 43, 1, p. 228-238 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Astrocyte 100%
  • Vacuolization 60%
  • White Matter 40%
  • Diseases 30%
  • Cells 30%

• Neurotrophic Effects of PACAP in the Cerebellar Cortex

  Falluel-Morel, A., Vaudry, H., Komuro, H., Gorecki, D., Galas, L. & Vaudry, D., 2011, Hormones in neurodegeneration, neuroprotection, and neurogenesis. Gravanis, A. & Mellon, S. (eds.). Weinheim: Wiley-VCH, p. 227-236 10 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

  • Hypophysis Adenylate Cyclase Activating Polypeptide 100%
  • Granule Cell 66%
  • Eicosanoid Receptor 16%
  • receptors 16%

• Rapid resolution liquid chromatography (RRLC) analysis for quality control of Rhodiola rosea roots and commercial standardized products

  Ma., Y-C., Wang, X-Q., Hou, F., Ma, J., Luo, M., Lu, S., Jin, P., Terevsky, N., Chen, A., Xu, I., Sautreau, A. & Gorecki, D., May 2011, In: Natural Product Communications. 6, 5, p. 645-650

  Research output: Contribution to journal › Article › peer-review

  • roots 100%
  • resolution 80%
  • liquid column chromatography 80%
  • Procedure 60%
  • powders 40%

• Simultaneous quantification of Echinacea species, Flos lonicerae, Radix scutellaria and Fructus forsythiae combinations by rapid resolution liquid chromatography

  Ma, J., Ma, Y., Cai, C., Wang, D., Hou, F., Luo, M., Lu, S., Gorecki, D., Sautreau, A., Chen, A. & Jin, P., 2011, In: Natural Product Communications. 6, 5, p. 639-643 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Scutellariae Radix 100%
  • Lonicera 100%
  • Nitrogen Mustard 50%
  • resolution 50%
  • ph value 50%