Research outputs per year
Research outputs per year
Personal profile
Biography
I run the The Dysglycaemia, Oxidative stress and the Vascular Endothelium (DOVE) Project which is a clinical collaboration between myself and the Academic Department of Diabetes and Endocrinology, Queen Alexandra Hospital (Portsmouth Hospitals NHS Trust), that aims to examine the roles and interactions of both traditional and non-traditional metabolic and cardiovascular risk factors in diabetes mellitus.
Research Interests
Oxidative stress, endothelial dysfunction, cardiovascular disease, diabetes mellitus, cystic fibrosis, copper aminoglycosides, antioxidants, organ preservation; Supervisor for postgraduate students at PhD and MD level; Clinical collaboration with Portsmouth Hospitals NHS Trust in diabetes (The Portsmouth Dysglycaemia, Oxidative Stress and the Vascular Endothelium (DOVE) Project).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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A randomised placebo controlled trial of VSL#3® probiotic on biomarkers of cardiovascular risk and liver injury in non-alcoholic fatty liver disease
Chong, P. L., Laight, D., Aspinall, R. J., Higginson, A. & Cummings, M. H., 1 Apr 2021, In: BMC Gastroenterology. 21, 1, p. 1-9 9 p., 144.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) in human lung microvascular endothelial cells controls oxidative stress, reactive oxygen-mediated cell signaling and inflammatory responses
Khalaf, M., Scott-Ward, T., Causer, A., Saynor, Z., Shepherd, A., Górecki, D., Lewis, A., Laight, D. & Shute, J., 29 Jul 2020, In: Frontiers in Physiology. 11, 20 p., 879.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Effects of collagen-derived bioactive peptides and natural antioxidant compounds on proliferation and matrix protein synthesis by cultured normal human dermal fibroblasts
Edgar, S., Hopley, B., Genovese, L., Sibilla, S., Laight, D. & Shute, J., 11 Jul 2018, In: Scientific Reports. 8, 10474.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The effects of garlic extract upon endothelial function, vascular inflammation, oxidative stress and insulin resistance in adults with type 2 diabetes at high cardiovascular risk: a pilot double blind randomized placebo controlled trial
Atkin, M., Laight, D. & Cummings, M. H., 1 May 2016, In: Journal of Diabetes and its Complications. 30, 4, p. 723-727 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The effects of tobramycin on pulmonary fibroblast function
Edgar, S., Laight, D. & Shute, J., 8 Sept 2016, p. PA4036.Research output: Contribution to conference › Abstract › peer-review
Open Access
Datasets
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Data availability statment for 'Effects of collagen-derived bioactive peptides and natural antioxidant compounds on proliferation and matrix protein synthesis by cultured normal human dermal fibroblasts'.
Edgar, S. (Creator), Hopley, B. G. T. (Creator), Genovese, L. (Creator), Sibilla, S. (Creator), Laight, D. (Creator) & Shute, J. (Creator), Springer Nature, 11 Jul 2018
Dataset