Matilda Clark

Matilda Clark


Personal profile



I started my PhD in the Centre for Enzyme Innovation in October 2020 under the supervision of Andy Pickford. During my PhD I have focused on characterising plastic degrading enzymes using structural, biochemical and biophysical techniques. My aim is to use this information to engineer enzymes which will have improved activity on an industrial scale. This involves characterising how different enzymes unfold and how this relates to their sequences. This could be used to engineer enzymes with increased stability and durability.  



I completed a BSc in Biochemistry (with year in industry) at the University of Leicester with a final year project in characterising therapeutic antibodies using NMR. I spent my year in industry at LifeArc (Stevenage) using biochemical and biophysical methods to investigate potentially therapeutic molecules.


Research Interests

Engineering enzymes for plastic depolymerisation

Enzyme durability under stress

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 9 - Industry, Innovation, and Infrastructure

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or