Research outputs per year
Research outputs per year
Personal profile
Summary
Summary
I started my PhD in the Centre for Enzyme Innovation in October 2020 under the supervision of Andy Pickford. During my PhD I have focused on characterising plastic degrading enzymes using structural, biochemical and biophysical techniques. My aim is to use this information to engineer enzymes which will have improved activity on an industrial scale. This involves characterising how different enzymes unfold and how this relates to their sequences. This could be used to engineer enzymes with increased stability and durability.
Biography
I completed a BSc in Biochemistry (with year in industry) at the University of Leicester with a final year project in characterising therapeutic antibodies using NMR. I spent my year in industry at LifeArc (Stevenage) using biochemical and biophysical methods to investigate potentially therapeutic molecules.
Research Interests
Engineering enzymes for plastic depolymerisation
Enzyme durability under stress
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
- 1 Article
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Concentration-dependent inhibition of mesophilic PETases on poly(ethylene terephthalate) can be eliminated by enzyme engineering
Avilan, L., Lichtenstein, B., Koenig, G., Zahn, M., Allen, M. D., Oliveira Pessoa, L., Clark, M. A., Bemmer, V. L., Graham, R., Austin, H. P., Dominick, G., Johnson, C. W., Beckham, G. T., McGeehan, J. & Pickford, A., 21 Feb 2023, (Early online) In: ChemSusChem.Research output: Contribution to journal › Article › peer-review