• United Kingdom

Accepting PhD Students

PhD projects

1. Implications of mitochondrial redox status and mitophagy in cancer cells’ survival 2. Assessing the Potential Value of Repurposing TCAs fro Treating Breast-to-Brain Metatase

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Personal profile

Biography

I am a molecular biologist with a major research interest in genetic abnormalities in human cancers as biomarkers for cancer diagnosis, prognosis and treatment. I gained a PhD in Molecular Oncology and completed my early post-doctoral training at Cancer Research UK and Southampton University, where my research on oxidative DNA damage led to a better clarification of the cytotoxic mechanism of the anti-cancer drug 5-FU. During that period I also established a model which may help to understand the molecular consequences of unbalanced translocations in human cancer. I joined the Neuro-oncology Research Group led by Prof. Geoff Pilkington at Portsmouth University in 2009 and became an HEFCE-funded Senior Research Fellow in 2013, then in 2016 I took on a Senior Lecturer post in the School of Pharmacy & Biomedical Sciences.  Currently I am investigating mitochondrial abnormalities in the development and progression of human cancers, novel therapeutic agents targeting mitochondria, the Gas6/Axl pathway in cancer, and underlying mechanisms of cancer survival/drug resistance.

For more information about my research please visit my lab page.

Research Interests

Mitochondrial abnormalities in the development and progression of human cancers

Novel therapeutic agents targeting mitochondria

Gas6/Axl pathway in cancer

Underlying mechanisms of cancer survival/drug resistance

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

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