Robbie Baldock

Search results

• 2024

  A comparative analysis of machine learning algorithms for detecting COVID-19 using lung X-ray images

  Hamal, S., Kumar Mishra, B., Baldock, R. A., Sayers, W., Narayan Adhikari, T. & Gibson, R. M., 9 Apr 2024, (Early online) In: Decision Analytics Journal. 100460.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  37 Downloads (Pure)

• Hydroquinine enhances the efficacy of contact lens solutions for inhibiting Pseudomonas aeruginosa adhesion and biofilm formation

  Weawsiangsang, S., Rattanachak, N., Ross, S., Ross, G., Baldock, R. A., Jongjitvimol, T. & Jongjitwimol, J., 5 Jan 2024, In: Antibiotics. 13, 1, 17 p., 56.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  35 Downloads (Pure)
• 2023

  A novel and quantitative detection assay (effluxR) for identifying efflux-associated resistance genes using multiplex digital PCR in clinical isolates of Pseudomonas aeruginosa

  Rattanachak, N., Weawsiangsang, S., Baldock, R. A., Jaifoo, T., Jongjitvimol, T. & Jongjitwimol, J., 8 Oct 2023, In: Methods and Protocols. 6, 5, 17 p., 96.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  54 Downloads (Pure)

• Hydroquinine: a potential new avenue in drug discovery for drug-resistant bacteria?

  Jongjitwimol, J. & Baldock, R. A., 6 Feb 2023, (Early online) In: Expert Opinion on Drug Discovery.

  Research output: Contribution to journal › Editorial › peer-review

  Open Access

• Hydroquinine inhibits the growth of multidrug-resistant pseudomonas aeruginosa via the suppression of the arginine deiminase pathway genes

  Weawsiangsang, S., Rattanachak, N., Jongjitvimol, T., Jaifoo, T., Charoensit, P., Viyoch, J., Ross, S., Ross, G. M., Baldock, R. A. & Jongjitwimol, J., 10 Sept 2023, In: International Journal of Molecular Sciences. 24, 18, 17 p., 19314.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  45 Downloads (Pure)
• 2022

  Fluoroquinolones: old drugs, putative new toxicities

  Bove, C., Baldock, R. A., Champigneulle, O., Martin, L. & Bennett, C. L., 22 Nov 2022, In: Expert Opinion on Drug Safety. 21, 11, p. 1365-1378

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Quinolone Derivative 100%
  • canada 42%
  • australia 42%
  • new zealand 42%
  • japan 42%
  182 Downloads (Pure)

• High-throughput transcriptomic profiling reveals the inhibitory effect of hydroquinine on virulence factors in Pseudomonas aeruginosa

  Rattanachak, N., Weawsiangsang, S., Daowtak, K., Thongsri, Y., Ross, S., Ross, G., Nilsri, N., Baldock, R. A., Pongcharoen, S., Jongjitvimol, T. & Jongjitwimol, J., 19 Oct 2022, In: Antibiotics. 11, 10, 16 p., 1436.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Hydroquinine 100%
  • Pseudomonas aeruginosa 55%
  • genes 55%
  • Quantitative Reverse Transcription Polymerase Chain Reaction 44%
  • Gene 44%
  50 Downloads (Pure)

• Hydroquinine possesses antibacterial activity, and at half the MIC, induces the overexpression of RND-type efflux pumps using multiplex digital PCR in pseudomonas aeruginosa

  Rattanachak, N., Weawsiangsang, S., Jongjitvimol, T., Baldock, R. A. & Jongjitwimol, J., 30 Jul 2022, In: Tropical Medicine and Infectious Disease. 7, 8, 14 p., 156.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Antibacterial Activity 100%
  • Minimum Inhibitory Concentration 100%
  • Pseudomonas aeruginosa 100%
  • Transcriptomics 66%
  • Electric Potential 66%
  73 Downloads (Pure)

• Integrating Augmented Reality into bioscience education

  Baldock, R. A., 2 Jun 2022, FEBS Network.

  Research output: Contribution to specialist publication › Article

  Open Access

  • Education 100%
  • Augmented Reality 100%
  • education 100%
  • Visualization 50%
  • Complexity 50%
• 2021

  Beyond base excision repair: an evolving picture of mitochondrial DNA repair

  Allkanjari, K. & Baldock, R. A., 14 Oct 2021, In: Bioscience Reports. 41, 10, 14 p., BSR20211320.

  Research output: Contribution to journal › Literature review › peer-review

  Open Access

  File

  • mitochondria 100%
  • dna 33%
  • Mitochondrion 33%
  • Mitochondrial DNA 33%
  • repair 26%
  59 Downloads (Pure)

• DNA repair and gene editing: the director’s cut

  Doughty, K. & Baldock, R. A., 1 Dec 2021, The Biochemist, 43, 6, p. 16-20 5 p.

  Research output: Contribution to specialist publication › Article

  Open Access

  File
  74 Downloads (Pure)

• RAD51 paralog function in replicative DNA damage and tolerance

  Rein, H. L., Bernstein, K. A. & Baldock, R. A., 1 Dec 2021, In: Current Opinion in Genetics and Development. 71, p. 86-91 6 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Paralogy 100%
  • RAD51 100%
  • DNA Replication 25%
  • Stress 25%
  • tolerance 25%
  135 Downloads (Pure)

• Use of augmented reality (AR) to aid bioscience education and enrich student experience

  Reeves, L. E., Bolton, E., Bulpitt, M., Scott, A., Tomey, I., Gates, M. & Baldock, R. A., 15 Jan 2021, In: Research in Learning Technology. 29, 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Augmented Reality 100%
  • cost 33%
  • Virtual Reality 22%
  • User Experience 22%
  • learning 22%
  22 Downloads (Pure)
• 2020

  Coronavirus ‘cytokine storm’: this over-active immune response could be behind some fatal cases of COVID-19

  Baldock, R. A., 28 Apr 2020, The Conversation.

  Research output: Contribution to specialist publication › Article

  Open Access

  • COVID-19 100%
  • covid-19 50%
  • Fatality 33%
  • Cytokine Storm 33%
  • Person 33%

• Data Collection using Webscraping

  Baldock, R. A., 11 Nov 2020

  Research output: Other contribution › Blog posts

  Open Access

  • data 100%
  • programming 50%
  • Data Collection 50%
• 2019

  Evolution-based screening enables genome-wide prioritization and discovery of DNA repair genes

  Brunette, G. J., Jamalruddin, M. A., Baldock, R. A., Clark, N. L. & Bernstein, K. A., 24 Sept 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 39, p. 19593-19599 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • dna repair 100%
  • DNA Repair 100%
  • genes 83%
  • Nested Gene 66%
  • apoptosis 50%

• Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint

  Bigot, N., Day, M., Baldock, R. A., Watts, F. Z., Oliver, A. W. & Pearl, L. H., 28 May 2019, In: eLife. 8, 28 p., e44353.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • dna damages 100%
  • interactions 80%
  • phosphorylation 80%
  • Phosphorylation 80%
  • DNA Damage Checkpoint 60%
  45 Downloads (Pure)

• RAD51D splice variants and cancer-associated mutations reveal XRCC2 interaction to be critical for homologous recombination

  Baldock, R. A., Pressimone, C. A., Baird, J. M., Khodakov, A., Luong, T. T., Grundy, M. K., Smith, C. M., Karpenshif, Y., Bratton-Palmer, D. S., Prakash, R., Jasin, M., Garcin, E. B., Gon, S., Modesti, M. & Bernstein, K. A., 1 Apr 2019, In: DNA repair. 76, p. 99-107 9 p.

  Research output: Contribution to journal › Article › peer-review

  • cancer 100%
  • mutations 100%
  • Mutation 100%
  • interactions 85%
  • gene recombination 71%
• 2018

  Drosha drives the formation of DNA:RNA hybrids around DNA break sites to facilitate DNA repair

  Lu, W-T., Hawley, B. R., Skalka, G. L., Baldock, R. A., Smith, E. M., Bader, A. S., Malewicz, M., Watts, F. Z., Wilczynska, A. & Bushell, M., 7 Feb 2018, In: Nature Communications. 9, 1, 13 p., 532.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • rna 100%
  • dna 83%
  • Drosha 83%
  • repair 66%
  • RNA 66%
  51 Downloads (Pure)
• 2016

  Human BRCA1-BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection

  Densham, R. M., Garvin, A. J., Stone, H. R., Strachan, J., Baldock, R. A., Daza-Martin, M., Fletcher, A., Blair-Reid, S., Beesley, J., Johal, B., Pearl, L. H., Neely, R., Keep, N. H., Watts, F. Z. & Morris, J. R., 1 Jul 2016, In: Nature Structural & Molecular Biology. 23, 7, p. 647-655 9 p.

  Research output: Contribution to journal › Article › peer-review

  • BRCA1 100%
  • BARD1 87%
  • Ubiquitin 50%
  • DNA 50%
  • chromatin 50%

• Sumoylation of eIF4A2 affects stress granule formation

  Jongjitwimol, J., Baldock, R. A., Morley, S. J. & Watts, F. Z., 15 Jun 2016, In: Journal of Cell Science. 129, 12, p. 2407-2415 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Sumoylation 100%
  • Stress Granule 83%
  • Translation Initiation 33%
  • Arsenite 33%
  • Initiation Factor 33%
  84 Downloads (Pure)
• 2015

  ATM localization and heterochromatin repair depend on direct interaction of the 53BP1-BRCT₂ domain with γH2AX

  Baldock, R. A., Day, M., Wilkinson, O. J., Cloney, R., Jeggo, P. A., Oliver, A. W., Watts, F. Z. & Pearl, L. H., 15 Dec 2015, In: Cell Reports. 13, 10, p. 2081-2089 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • repair 100%
  • interactions 75%
  • heterochromatin 75%
  • dna damages 75%
  • Heterochromatin 75%
  48 Downloads (Pure)
• 2014

  The S. pombe translation initiation factor eIF4G is Sumoylated and associates with the SUMO protease Ulp2

  Jongjitwimol, J., Feng, M., Zhou, L., Wilkinson, O., Small, L., Baldock, R., Taylor, D. L., Smith, D., Bowler, L. D., Morley, S. J. & Watts, F. Z., 12 May 2014, In: PLoS One. 9, 5, 13 p., e94182.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • proteins 100%
  • Protein 50%
  • Proteases 30%
  • Protein-Protein Interaction 20%
  • Translation Initiation 20%
  35 Downloads (Pure)

• Weighing up the possibilities: controlling translation by ubiquitylation and sumoylation

  Watts, F. Z., Baldock, R., Jongjitwimol, J. & Morley, S. J., 1 Nov 2014, In: Translation. 2, 2, 11 p., e959366.

  Research output: Contribution to journal › Literature review › peer-review

  Open Access

  File

  • proteins 100%
  • Ubiquitin 66%
  • synthesis 50%
  • messenger-rna 50%
  • Protein Biosynthesis 50%
  34 Downloads (Pure)