Mapping the information entropy spectrum of genomes

Project Details

Description

GENIES is a computer program developed to facilitate the study of genome sequences in a comparative way using the information entropy. The program can analyse genomes of any size by converting the genetic information contained in a given genome into a numerical Information Entropy Spectrum. This procedure is done for two genomes of the same size, one being a reference genome and the other being its mutated version. The program allows fast detection of base point mutations from the Information Entropy Spectra. Most importantly, the program could be used to research and identify predictive algorithms of future genetic mutations.

Layman's description

A mathematical - Information Theory method applied to the study of genetic sequences.

Key findings

Mutations detections in genomes including Covid-19 RNA and development of predictive algorithms of future genetic mutations.
AcronymGENIES
StatusActive
Effective start/end date1/05/20 → …

UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Keywords

  • Information theory
  • bio-informatics
  • Genetics research
  • COVID-19
  • physics of information
  • Information entropy

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