Acupuncture has traditionally been used for problems including anxiety, insomnia, stress, and depression in China and other East Asian countries. A range of different neurobiological responses to acupuncture have been investigated including modulation of serotonergic, noradrenergic, and dopaminergic systems; effects on GABA and the hypothalamic–pituitary–adrenal axis; and inflammatory responses. Interpretation of the findings is challenging because the neurobiology of psychiatric disorders has yet to be fully elucidated. Limitations also arise from the use of animal models and the selection of appropriate control treatments. Further complexity is added by acupuncture treatment being nonstandardized with acupuncture points often selected on the basis on traditional practice and theory. Potentially promising findings require further investigation and substantiation.
|Title of host publication||Neurobiology of Acupuncture|
|Editors||Bai-Yun Zeng, Kaicun Zhao, Fan-Rong Liang|
|Number of pages||20|
|Publication status||Published - 8 Nov 2013|
|Name||International Review of Neurobiology|
- psychiatric disorders
- substance abuse