TY - JOUR
T1 - Adsorbed pluronics on the skin of human volunteers
T2 - Effects on bacterial adhesion
AU - Marsh, Lorraine H.
AU - Alexander, Cameron
AU - Coke, Mark
AU - Dettmar, Peter W.
AU - Havler, Michael
AU - Nevell, Thomas G.
AU - Smart, John D.
AU - Timmins, Barry
AU - Tsibouklis, John
PY - 2003/1/30
Y1 - 2003/1/30
N2 - An amphiphilic copolymer, Pluronic F127, has been deposited, by adsorption, to the skin of human volunteers and the ability of the coated skin to resist bacterial colonisation has been evaluated. In parallel, the ability of the same copolymer to act as a bacterial release agent has been evaluated. In both cases, F127 proved to be of little added value in formulations designed to suppress the bacterial colonisation of human skin.
AB - An amphiphilic copolymer, Pluronic F127, has been deposited, by adsorption, to the skin of human volunteers and the ability of the coated skin to resist bacterial colonisation has been evaluated. In parallel, the ability of the same copolymer to act as a bacterial release agent has been evaluated. In both cases, F127 proved to be of little added value in formulations designed to suppress the bacterial colonisation of human skin.
KW - Bacterial-release coatings
KW - In vivo evaluation
KW - Pluronic F127
UR - http://www.scopus.com/inward/record.url?scp=0037472338&partnerID=8YFLogxK
U2 - 10.1016/S0378-5173(02)00592-6
DO - 10.1016/S0378-5173(02)00592-6
M3 - Article
C2 - 12527185
AN - SCOPUS:0037472338
VL - 251
SP - 155
EP - 163
JO - International Journal of Pharmaceutics
JF - International Journal of Pharmaceutics
SN - 0378-5173
IS - 1-2
ER -