Association between micronutrient levels and chronic spontaneous urticaria

Cheng-Han Wu; Efrem Eren; Michael Roger Ardern-Jones; Carina Venter

doi:10.1155/2015/926167

Association between micronutrient levels and chronic spontaneous urticaria

Cheng-Han Wu, Efrem Eren, Michael Roger Ardern-Jones, Carina Venter

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Abstract

Previous reports have suggested a possible role for vitamin D in the etiology of chronic spontaneous urticaria (CSU); however, little information is available regarding the role of other micronutrients. We, therefore, analyzed vitamin D, vitamin B12, and ferritin levels in CSU patients (n=282) from a preexisting database at Southampton General Hospital. Data were compared against mean micronutrient levels of the general population of the UK, obtained from the National Diet and Nutrition Survey. Vitamin D levels of CSU patients were found to be higher than those of the general UK population (P = 0.001). B12 levels were lower in patients with CSU (P < 0.001) than in the general population. Ferritin levels were found to be lower in male CSU patients than in the general male population (P = 0.009). This association between low B12 and iron levels and CSU might indicate a causal link, with micronutrient replacement as a potential therapeutic option.

Original language	English
Article number	926167
Pages (from-to)	1-3
Number of pages	3
Journal	BioMed Research International
Volume	2015
DOIs	https://doi.org/10.1155/2015/926167
Publication status	Published - 2015

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Association between Micronutrient LevelsFinal published version, 1.17 MBLicence: CC BY

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title = "Association between micronutrient levels and chronic spontaneous urticaria",

abstract = "Previous reports have suggested a possible role for vitamin D in the etiology of chronic spontaneous urticaria (CSU); however, little information is available regarding the role of other micronutrients. We, therefore, analyzed vitamin D, vitamin B12, and ferritin levels in CSU patients (n=282) from a preexisting database at Southampton General Hospital. Data were compared against mean micronutrient levels of the general population of the UK, obtained from the National Diet and Nutrition Survey. Vitamin D levels of CSU patients were found to be higher than those of the general UK population (P = 0.001). B12 levels were lower in patients with CSU (P < 0.001) than in the general population. Ferritin levels were found to be lower in male CSU patients than in the general male population (P = 0.009). This association between low B12 and iron levels and CSU might indicate a causal link, with micronutrient replacement as a potential therapeutic option.",

author = "Cheng-Han Wu and Efrem Eren and Ardern-Jones, {Michael Roger} and Carina Venter",

year = "2015",

doi = "10.1155/2015/926167",

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T1 - Association between micronutrient levels and chronic spontaneous urticaria

AU - Wu, Cheng-Han

AU - Eren, Efrem

AU - Ardern-Jones, Michael Roger

AU - Venter, Carina

PY - 2015

Y1 - 2015

N2 - Previous reports have suggested a possible role for vitamin D in the etiology of chronic spontaneous urticaria (CSU); however, little information is available regarding the role of other micronutrients. We, therefore, analyzed vitamin D, vitamin B12, and ferritin levels in CSU patients (n=282) from a preexisting database at Southampton General Hospital. Data were compared against mean micronutrient levels of the general population of the UK, obtained from the National Diet and Nutrition Survey. Vitamin D levels of CSU patients were found to be higher than those of the general UK population (P = 0.001). B12 levels were lower in patients with CSU (P < 0.001) than in the general population. Ferritin levels were found to be lower in male CSU patients than in the general male population (P = 0.009). This association between low B12 and iron levels and CSU might indicate a causal link, with micronutrient replacement as a potential therapeutic option.

AB - Previous reports have suggested a possible role for vitamin D in the etiology of chronic spontaneous urticaria (CSU); however, little information is available regarding the role of other micronutrients. We, therefore, analyzed vitamin D, vitamin B12, and ferritin levels in CSU patients (n=282) from a preexisting database at Southampton General Hospital. Data were compared against mean micronutrient levels of the general population of the UK, obtained from the National Diet and Nutrition Survey. Vitamin D levels of CSU patients were found to be higher than those of the general UK population (P = 0.001). B12 levels were lower in patients with CSU (P < 0.001) than in the general population. Ferritin levels were found to be lower in male CSU patients than in the general male population (P = 0.009). This association between low B12 and iron levels and CSU might indicate a causal link, with micronutrient replacement as a potential therapeutic option.

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DO - 10.1155/2015/926167

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Association between micronutrient levels and chronic spontaneous urticaria

Abstract

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