Bacterial adsorption to thermoresponsive polymer surfaces

D. Cunliffe, C. A. Smart, J. Tsibouklis, S. Young, C. Alexander, E. N. Vulfson*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


The ability of microorganisms to 'recognise' a change in the hydrophobicity/hydrophilicity balance of the surface was demonstrated using thermoresponsive poly(N-isopropylacrylamide) co-polymers with different Lower Critical Solution Temperatures. The polymers were grafted onto hydrolysed glass under well controlled conditions and the adhesion was followed using 13C-labelled Listeria monocytogenes. Attachment of the bacteria was found to be directly affected by the polymer transition from a hydrophilic to a hydrophobic state but by less than one order of magnitude.

Original languageEnglish
Pages (from-to)141-145
Number of pages5
JournalBiotechnology Letters
Issue number2
Publication statusPublished - 1 Jan 2000


  • Bacterial adhesion
  • Biocompatible surfaces
  • Lower Critical Solution Temperature
  • Polymers


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