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Bacterial adsorption to thermoresponsive polymer surfaces

  • D. Cunliffe
  • , C. A. Smart
  • , J. Tsibouklis
  • , S. Young
  • , C. Alexander
  • , E. N. Vulfson*
  • *Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

The ability of microorganisms to 'recognise' a change in the hydrophobicity/hydrophilicity balance of the surface was demonstrated using thermoresponsive poly(N-isopropylacrylamide) co-polymers with different Lower Critical Solution Temperatures. The polymers were grafted onto hydrolysed glass under well controlled conditions and the adhesion was followed using 13C-labelled Listeria monocytogenes. Attachment of the bacteria was found to be directly affected by the polymer transition from a hydrophilic to a hydrophobic state but by less than one order of magnitude.

Original languageEnglish
Pages (from-to)141-145
Number of pages5
JournalBiotechnology Letters
Volume22
Issue number2
DOIs
Publication statusPublished - 1 Jan 2000

Keywords

  • Bacterial adhesion
  • Biocompatible surfaces
  • Lower Critical Solution Temperature
  • Polymers

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