TY - JOUR
T1 - Biosynthesis and characterization of Acalypha indica mediated copper oxide nanoparticles and evaluation of its antimicrobial and anticancer activity
AU - Sivaraj, Rajeshwari
AU - Rahman, Pattanathu K.S.M.
AU - Rajiv, P.
AU - Narendhran, S.
AU - Venckatesh, R.
PY - 2014/8/14
Y1 - 2014/8/14
N2 - Copper oxide nanoparticles were synthesized by biological method using aqueous extract of Acalypha indica leaf and characterized by UV-visible spectroscopy, XRD, FT-IR, SEM TEM and EDX analysis. The synthesised particles were highly stable, spherical and particle size was in the range of 26-30 nm. The antimicrobial activity of A. indica mediated copper oxide nanoparticles was tested against selected pathogens. Copper oxide nanoparticles showed efficient antibacterial and antifungal effect against Escherichia coli, Pseudomonas fluorescens and Candida albicans. The cytotoxicity activity of A. indica mediated copper nanoparticles was evaluated by MTT assay against MCF-7 breast cancer cell lines and confirmed that copper oxide nanoparticles have cytotoxicity activity.
AB - Copper oxide nanoparticles were synthesized by biological method using aqueous extract of Acalypha indica leaf and characterized by UV-visible spectroscopy, XRD, FT-IR, SEM TEM and EDX analysis. The synthesised particles were highly stable, spherical and particle size was in the range of 26-30 nm. The antimicrobial activity of A. indica mediated copper oxide nanoparticles was tested against selected pathogens. Copper oxide nanoparticles showed efficient antibacterial and antifungal effect against Escherichia coli, Pseudomonas fluorescens and Candida albicans. The cytotoxicity activity of A. indica mediated copper nanoparticles was evaluated by MTT assay against MCF-7 breast cancer cell lines and confirmed that copper oxide nanoparticles have cytotoxicity activity.
KW - Acalypha indica
KW - Antimicrobial
KW - Biological method
KW - Copper oxide nanoparticles
KW - Cytotoxicity
UR - http://www.scopus.com/inward/record.url?scp=84899016627&partnerID=8YFLogxK
U2 - 10.1016/j.saa.2014.03.027
DO - 10.1016/j.saa.2014.03.027
M3 - Article
C2 - 24747845
AN - SCOPUS:84899016627
VL - 129
SP - 255
EP - 258
JO - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
JF - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
SN - 1386-1425
ER -
