Biosynthesis and characterization of Acalypha indica mediated copper oxide nanoparticles and evaluation of its antimicrobial and anticancer activity

Rajeshwari Sivaraj; Pattanathu K.S.M. Rahman; P. Rajiv; S. Narendhran; R. Venckatesh

doi:10.1016/j.saa.2014.03.027

Biosynthesis and characterization of Acalypha indica mediated copper oxide nanoparticles and evaluation of its antimicrobial and anticancer activity

Rajeshwari Sivaraj^*, Pattanathu K.S.M. Rahman, P. Rajiv, S. Narendhran, R. Venckatesh

^*Corresponding author for this work

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Copper oxide nanoparticles were synthesized by biological method using aqueous extract of Acalypha indica leaf and characterized by UV-visible spectroscopy, XRD, FT-IR, SEM TEM and EDX analysis. The synthesised particles were highly stable, spherical and particle size was in the range of 26-30 nm. The antimicrobial activity of A. indica mediated copper oxide nanoparticles was tested against selected pathogens. Copper oxide nanoparticles showed efficient antibacterial and antifungal effect against Escherichia coli, Pseudomonas fluorescens and Candida albicans. The cytotoxicity activity of A. indica mediated copper nanoparticles was evaluated by MTT assay against MCF-7 breast cancer cell lines and confirmed that copper oxide nanoparticles have cytotoxicity activity.

Original language	English
Pages (from-to)	255-258
Number of pages	234
Journal	Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
Volume	129
Early online date	28 Mar 2014
DOIs	https://doi.org/10.1016/j.saa.2014.03.027
Publication status	Published - 14 Aug 2014

Keywords

Acalypha indica
Antimicrobial
Biological method
Copper oxide nanoparticles
Cytotoxicity

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.saa.2014.03.027

http://tees.openrepository.com/tees/handle/10149/316024

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Green synthesis, 2D and 3D organisation of metal nanoparticles from Indian medicinal plants
Rahman, P. & Rajeshwari, S.
1/02/13 → 30/04/13
Project: Research

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@article{00d3a7eec5dc42ab8f4461b1509b662d,

title = "Biosynthesis and characterization of Acalypha indica mediated copper oxide nanoparticles and evaluation of its antimicrobial and anticancer activity",

abstract = "Copper oxide nanoparticles were synthesized by biological method using aqueous extract of Acalypha indica leaf and characterized by UV-visible spectroscopy, XRD, FT-IR, SEM TEM and EDX analysis. The synthesised particles were highly stable, spherical and particle size was in the range of 26-30 nm. The antimicrobial activity of A. indica mediated copper oxide nanoparticles was tested against selected pathogens. Copper oxide nanoparticles showed efficient antibacterial and antifungal effect against Escherichia coli, Pseudomonas fluorescens and Candida albicans. The cytotoxicity activity of A. indica mediated copper nanoparticles was evaluated by MTT assay against MCF-7 breast cancer cell lines and confirmed that copper oxide nanoparticles have cytotoxicity activity.",

keywords = "Acalypha indica, Antimicrobial, Biological method, Copper oxide nanoparticles, Cytotoxicity",

author = "Rajeshwari Sivaraj and Rahman, {Pattanathu K.S.M.} and P. Rajiv and S. Narendhran and R. Venckatesh",

year = "2014",

month = aug,

day = "14",

doi = "10.1016/j.saa.2014.03.027",

language = "English",

volume = "129",

pages = "255--258",

journal = "Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy",

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publisher = "Elsevier",

}

Biosynthesis and characterization of Acalypha indica mediated copper oxide nanoparticles and evaluation of its antimicrobial and anticancer activity. / Sivaraj, Rajeshwari; Rahman, Pattanathu K.S.M.; Rajiv, P.; Narendhran, S.; Venckatesh, R.

In: Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, Vol. 129, 14.08.2014, p. 255-258.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Biosynthesis and characterization of Acalypha indica mediated copper oxide nanoparticles and evaluation of its antimicrobial and anticancer activity

AU - Sivaraj, Rajeshwari

AU - Rahman, Pattanathu K.S.M.

AU - Rajiv, P.

AU - Narendhran, S.

AU - Venckatesh, R.

PY - 2014/8/14

Y1 - 2014/8/14

N2 - Copper oxide nanoparticles were synthesized by biological method using aqueous extract of Acalypha indica leaf and characterized by UV-visible spectroscopy, XRD, FT-IR, SEM TEM and EDX analysis. The synthesised particles were highly stable, spherical and particle size was in the range of 26-30 nm. The antimicrobial activity of A. indica mediated copper oxide nanoparticles was tested against selected pathogens. Copper oxide nanoparticles showed efficient antibacterial and antifungal effect against Escherichia coli, Pseudomonas fluorescens and Candida albicans. The cytotoxicity activity of A. indica mediated copper nanoparticles was evaluated by MTT assay against MCF-7 breast cancer cell lines and confirmed that copper oxide nanoparticles have cytotoxicity activity.

AB - Copper oxide nanoparticles were synthesized by biological method using aqueous extract of Acalypha indica leaf and characterized by UV-visible spectroscopy, XRD, FT-IR, SEM TEM and EDX analysis. The synthesised particles were highly stable, spherical and particle size was in the range of 26-30 nm. The antimicrobial activity of A. indica mediated copper oxide nanoparticles was tested against selected pathogens. Copper oxide nanoparticles showed efficient antibacterial and antifungal effect against Escherichia coli, Pseudomonas fluorescens and Candida albicans. The cytotoxicity activity of A. indica mediated copper nanoparticles was evaluated by MTT assay against MCF-7 breast cancer cell lines and confirmed that copper oxide nanoparticles have cytotoxicity activity.

KW - Acalypha indica

KW - Antimicrobial

KW - Biological method

KW - Copper oxide nanoparticles

KW - Cytotoxicity

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U2 - 10.1016/j.saa.2014.03.027

DO - 10.1016/j.saa.2014.03.027

M3 - Article

C2 - 24747845

AN - SCOPUS:84899016627

VL - 129

SP - 255

EP - 258

JO - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

JF - Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

SN - 1386-1425

ER -

Biosynthesis and characterization of Acalypha indica mediated copper oxide nanoparticles and evaluation of its antimicrobial and anticancer activity

Abstract

Keywords

UN SDGs

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Projects

Green synthesis, 2D and 3D organisation of metal nanoparticles from Indian medicinal plants

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