The bone cell formation on a photochemically etched Titanium alloy surface was investigated. Three microgrooved titanium alloy fine, medium and coarse were created by photochemical etching. Human mesenchymal stem cells (MSC) and human osteosarcoma (HOS) cells were seeded onto these surfaces and cultured in standard media. In vitro, all cells showed an increase in proliferation with time, the greatest occurring on the coarse surfaces. Scanning electron microscopy showed uniform attachment and distribution of HOS cells across the textured and smooth surface revealing no biocompatibility problem. The results show that the rate of differentiation of these cells increases significantly in relation to the size of the grooves.
|Title of host publication
|7th World Biomaterials Congress Congress 2004
|Curran Associates, Inc.
|Number of pages
|Published - 1 Apr 2006
|Transactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 17 May 2004 → 21 May 2004
|Transactions - 7th World Biomaterials Congress
|17/05/04 → 21/05/04