C1-TEN is a negative regulator of the Akt/PKB signal transduction pathway and inhibits cell survival, proliferation, and migration

Sassan Hafizi; F. Ibraimi; B. Dahlback

doi:10.1096/fj.04-2532fje

C1-TEN is a negative regulator of the Akt/PKB signal transduction pathway and inhibits cell survival, proliferation, and migration

Sassan Hafizi, F. Ibraimi, B. Dahlback

Research output: Contribution to journal › Article › peer-review

Abstract

We have investigated the effects of overexpression of a novel intracellular molecule, C1 domain-containing phosphatase and TENsin homologue (C1-TEN), on the phenotypic and intracellular signal transduction properties of mammalian HEK293 cells.

Original language	English
Pages (from-to)	971-973
Number of pages	3
Journal	FASEB Journal
Volume	19
Issue number	8
DOIs	https://doi.org/10.1096/fj.04-2532fje
Publication status	Published - 2005

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title = "C1-TEN is a negative regulator of the Akt/PKB signal transduction pathway and inhibits cell survival, proliferation, and migration",

abstract = "We have investigated the effects of overexpression of a novel intracellular molecule, C1 domain-containing phosphatase and TENsin homologue (C1-TEN), on the phenotypic and intracellular signal transduction properties of mammalian HEK293 cells.",

author = "Sassan Hafizi and F. Ibraimi and B. Dahlback",

year = "2005",

doi = "10.1096/fj.04-2532fje",

language = "English",

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journal = "FASEB Journal",

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T1 - C1-TEN is a negative regulator of the Akt/PKB signal transduction pathway and inhibits cell survival, proliferation, and migration

AU - Hafizi, Sassan

AU - Ibraimi, F.

AU - Dahlback, B.

PY - 2005

Y1 - 2005

N2 - We have investigated the effects of overexpression of a novel intracellular molecule, C1 domain-containing phosphatase and TENsin homologue (C1-TEN), on the phenotypic and intracellular signal transduction properties of mammalian HEK293 cells.

AB - We have investigated the effects of overexpression of a novel intracellular molecule, C1 domain-containing phosphatase and TENsin homologue (C1-TEN), on the phenotypic and intracellular signal transduction properties of mammalian HEK293 cells.

U2 - 10.1096/fj.04-2532fje

DO - 10.1096/fj.04-2532fje

M3 - Article

SN - 0892-6638

VL - 19

SP - 971

EP - 973

JO - FASEB Journal

JF - FASEB Journal

IS - 8

ER -

C1-TEN is a negative regulator of the Akt/PKB signal transduction pathway and inhibits cell survival, proliferation, and migration

Abstract

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