Captopril: a free radical scavenger

M. Chopra*, N. Scott, J. McMurray, J. McLay, A. Bridges, W. E. Smith, J. J. Belch

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


The use of captopril in heart failure and hypertension is becoming increasingly accepted. Captopril has a sulphydryl group in its molecular structure. We wondered if this might confer free radical scavenging activity on the drug and have investigated this in an in vitro system. Results show that captopril is a free radical scavenger and we suggest that this action might be relevant in its use in heart failure and other vascular diseases. 1989 The British Pharmacological Society

Original languageEnglish
Pages (from-to)396-399
Number of pages4
JournalBritish Journal of Clinical Pharmacology
Issue number3
Publication statusPublished - 1 Mar 1989


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