Captopril: a free radical scavenger

M. Chopra; N. Scott; J. McMurray; J. McLay; A. Bridges; W. E. Smith; J. J. Belch

doi:10.1111/j.1365-2125.1989.tb05384.x

Captopril: a free radical scavenger

M. Chopra^*, N. Scott, J. McMurray, J. McLay, A. Bridges, W. E. Smith, J. J. Belch

^*Corresponding author for this work

School of Pharmacy & Biomedical Sciences

University of Dundee

Research output: Contribution to journal › Article › peer-review

Abstract

The use of captopril in heart failure and hypertension is becoming increasingly accepted. Captopril has a sulphydryl group in its molecular structure. We wondered if this might confer free radical scavenging activity on the drug and have investigated this in an in vitro system. Results show that captopril is a free radical scavenger and we suggest that this action might be relevant in its use in heart failure and other vascular diseases. 1989 The British Pharmacological Society

Original language	English
Pages (from-to)	396-399
Number of pages	4
Journal	British Journal of Clinical Pharmacology
Volume	27
Issue number	3
DOIs	https://doi.org/10.1111/j.1365-2125.1989.tb05384.x
Publication status	Published - 1 Mar 1989

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10.1111/j.1365-2125.1989.tb05384.x

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AU - Belch, J. J.

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Captopril: a free radical scavenger

Abstract

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