Changes in lung function during exercise are independently mediated by increases in deep body temperature

Mike Tipton, Pippa Kadinopoulos, Dan Roiz de Sa, Martin James Barwood

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Background - This study examined whether an increase in deep body temperature contributes to increases in ventilatory flow indicative of bronchodilatation.

Method - The study employed a within-participant repeated measures design. Nine participants (mean [SD]: age 22 [3] years; height 177.7 [8.3] cm; mass 80.2 [19.1] kg) completed three conditions: Exercise (EXERC; 30 minutes); 40 °C water immersion (IMM40; 30 minutes) to passively raise rectal temperature (Trec); and 35 °C immersion (IMM35; 30 minutes) a thermoneutral control for IMM40. A forced vital capacity (FVC) manoeuvre was performed at the start of the test and every 10 minutes thereafter. Forced expiratory volume in one second [FEV1] FEV1/FVC, 25, 50 and 75 % maximal expiratory flow during FVC (FEF75, FEF50, FEF25) were also measured. Data were compared using a repeated measures two-way ANOVA, with a 0.05 alpha level.

Results - Rectal temperature (Trec) peaked after 30 minutes in the EXERC (mean [SD] 38.0 [0.3] °C) and IMM40 (38.2 [0.2] °C) conditions and were higher (P<0.05) than that those at the corresponding time in the thermoneutral condition (37.2 [0.2] °C). At this time FEV1 was 4.5 (0.6), 4.6 (0.3), and 4.4 (0.6) L respectively. Trec, FEV1, and FEV1/FVC were greater in the IMM40 and EXERC conditions compared to the IMM35 condition. Interaction effects were evident for FEF50 and FEF75 (P<0.05), being higher in IMM40 and EXERC conditions.

Conclusion - Increasing deep body temperature, independently, contributes to the increased airflow ascribed to bronchodilatation when exercising.
Original languageEnglish
Article numbere000210
JournalBMJ Open Sport and Exercise Medicine
Issue number1
Early online date2 Jun 2017
Publication statusPublished - Jul 2017


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