Clostridial whole cell and enzyme systems for hydrogen production: current state and perspectives

Amel Latifi, Luisana Avilan, Myriam Brugna

Research output: Contribution to journalReview articlepeer-review


Strictly anaerobic bacteria of the Clostridium genus have attracted great interest as potential cell factories for molecular hydrogen production purposes. In addition to being a useful approach to this process, dark fermentation has the advantage of using the degradation of cheap agricultural residues and industrial wastes for molecular hydrogen production. However, many improvements are still required before large-scale hydrogen production from clostridial metabolism is possible. Here we review the literature on the basic biological processes involved in clostridial hydrogen production, and present the main advances obtained so far in order to enhance the hydrogen productivity, as well as suggesting some possible future prospects.

Original languageEnglish
Pages (from-to)567-575
Number of pages9
JournalApplied Microbiology and Biotechnology
Issue number2
Early online date17 Nov 2018
Publication statusPublished - 18 Jan 2019


  • Anaerobiosis
  • Clostridium/enzymology
  • Fermentation
  • Hydrogen/metabolism
  • Industrial Waste


Dive into the research topics of 'Clostridial whole cell and enzyme systems for hydrogen production: current state and perspectives'. Together they form a unique fingerprint.

Cite this