Comparative finite element modelling of aneurysm formation and physiologic inflation in the descending aorta

Serena de Gelidi, Andrea Bucchi*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

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Abstract

Despite the general interest in aneurysm rupture prediction, the aneurysm formation has received limited attention. The goal of this study is to assess whether an aneurysm may be instigated in a healthy model of an aorta inflated by a supra-physiological pressure. The effect of two main aspects on numerical predictions has been explored: i) the geometric design and ii) the constitutive law adopted to represent the material properties. Firstly, higher values of wall stress and displacement magnitude were generated in the physiologic model compared to the cylindrical one when assigning the same material properties. Secondly, greater deformations are observed in the anisotropic model compared to the isotropic one.

Original languageEnglish
Pages (from-to)1197-1208
Number of pages12
JournalComputer Methods in Biomechanics and Biomedical Engineering
Volume22
Issue number15
Early online date21 Aug 2019
DOIs
Publication statusPublished - 1 Nov 2019

Keywords

  • aneurysm
  • anisotropic
  • aorta
  • finite element
  • Fung
  • RCUK
  • EPSRC
  • EP/M014711/1

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