Comparison of LDL fatty acid and carotenoid concentrations and oxidative resistance of LDL in volunteers from countries with different rates of cardiovascular disease

Anthony J. A. Wright; Susan Southon; Mridula Chopra; Anita Meyer-Wenger; Ulrich Moser; Fernando Granado; Begona Olmedilla; Bernice Corridan; Isabelle Hininger; Anne-Marie Roussel; Henk van den Berg; David I. Thurnham

doi:10.1079/BJN2001484

Comparison of LDL fatty acid and carotenoid concentrations and oxidative resistance of LDL in volunteers from countries with different rates of cardiovascular disease

Anthony J. A. Wright, Susan Southon, Mridula Chopra, Anita Meyer-Wenger, Ulrich Moser, Fernando Granado, Begona Olmedilla, Bernice Corridan, Isabelle Hininger, Anne-Marie Roussel, Henk van den Berg, David I. Thurnham

Institute of Life Sciences and Healthcare

Research output: Contribution to journal › Article › peer-review

Abstract

Within Europe there are differences in cardiovascular disease (CVD) risk between countries and this might be related to dietary habits. Oxidative modification of LDL is suggested to increase the risk of CVD and both the fatty acid and antioxidant content of LDL can affect its oxidation. In the present study, concentration of LDL fatty acid and antioxidant micronutrients (tocopherols and carotenoids) and ex vivo oxidative resistance of LDL (lag phase) was compared in volunteers from five countries with different fruit and vegetable intakes and reported rates of CVD. Eighty volunteers (forty males, forty females per centre), age range 25–45 years, were recruited from France, Northern Ireland, UK, Republic of Ireland, The Netherlands, and Spain, and their LDL composition and lag phase were measured. There were some differences in LDL carotenoid and α-tocopherol concentrations between countries. α-Tocopherol was low and β- + γ-tocopherol were high (P

Original language	English
Pages (from-to)	21-29
Number of pages	9
Journal	British Journal of Nutrition
Volume	87
Issue number	1
DOIs	https://doi.org/10.1079/BJN2001484
Publication status	Published - Jan 2002

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Wright, A. J. A., Southon, S., Chopra, M., Meyer-Wenger, A., Moser, U., Granado, F., Olmedilla, B., Corridan, B., Hininger, I., Roussel, A.-M., van den Berg, H., & Thurnham, D. I. (2002). Comparison of LDL fatty acid and carotenoid concentrations and oxidative resistance of LDL in volunteers from countries with different rates of cardiovascular disease. British Journal of Nutrition, 87(1), 21-29. https://doi.org/10.1079/BJN2001484

@article{65c0a1fa6eca4bd694b60e14d9bbadfd,

title = "Comparison of LDL fatty acid and carotenoid concentrations and oxidative resistance of LDL in volunteers from countries with different rates of cardiovascular disease",

abstract = "Within Europe there are differences in cardiovascular disease (CVD) risk between countries and this might be related to dietary habits. Oxidative modification of LDL is suggested to increase the risk of CVD and both the fatty acid and antioxidant content of LDL can affect its oxidation. In the present study, concentration of LDL fatty acid and antioxidant micronutrients (tocopherols and carotenoids) and ex vivo oxidative resistance of LDL (lag phase) was compared in volunteers from five countries with different fruit and vegetable intakes and reported rates of CVD. Eighty volunteers (forty males, forty females per centre), age range 25–45 years, were recruited from France, Northern Ireland, UK, Republic of Ireland, The Netherlands, and Spain, and their LDL composition and lag phase were measured. There were some differences in LDL carotenoid and α-tocopherol concentrations between countries. α-Tocopherol was low and β- + γ-tocopherol were high (P",

author = "Wright, {Anthony J. A.} and Susan Southon and Mridula Chopra and Anita Meyer-Wenger and Ulrich Moser and Fernando Granado and Begona Olmedilla and Bernice Corridan and Isabelle Hininger and Anne-Marie Roussel and {van den Berg}, Henk and Thurnham, {David I.}",

year = "2002",

month = jan,

doi = "10.1079/BJN2001484",

language = "English",

volume = "87",

pages = "21--29",

journal = "British Journal of Nutrition",

issn = "0007-1145",

publisher = "Cambridge University Press",

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Wright, AJA, Southon, S, Chopra, M, Meyer-Wenger, A, Moser, U, Granado, F, Olmedilla, B, Corridan, B, Hininger, I, Roussel, A-M, van den Berg, H & Thurnham, DI 2002, 'Comparison of LDL fatty acid and carotenoid concentrations and oxidative resistance of LDL in volunteers from countries with different rates of cardiovascular disease', British Journal of Nutrition, vol. 87, no. 1, pp. 21-29. https://doi.org/10.1079/BJN2001484

Comparison of LDL fatty acid and carotenoid concentrations and oxidative resistance of LDL in volunteers from countries with different rates of cardiovascular disease. / Wright, Anthony J. A.; Southon, Susan; Chopra, Mridula et al.
In: British Journal of Nutrition, Vol. 87, No. 1, 01.2002, p. 21-29.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Comparison of LDL fatty acid and carotenoid concentrations and oxidative resistance of LDL in volunteers from countries with different rates of cardiovascular disease

AU - Wright, Anthony J. A.

AU - Southon, Susan

AU - Chopra, Mridula

AU - Meyer-Wenger, Anita

AU - Moser, Ulrich

AU - Granado, Fernando

AU - Olmedilla, Begona

AU - Corridan, Bernice

AU - Hininger, Isabelle

AU - Roussel, Anne-Marie

AU - van den Berg, Henk

AU - Thurnham, David I.

PY - 2002/1

Y1 - 2002/1

N2 - Within Europe there are differences in cardiovascular disease (CVD) risk between countries and this might be related to dietary habits. Oxidative modification of LDL is suggested to increase the risk of CVD and both the fatty acid and antioxidant content of LDL can affect its oxidation. In the present study, concentration of LDL fatty acid and antioxidant micronutrients (tocopherols and carotenoids) and ex vivo oxidative resistance of LDL (lag phase) was compared in volunteers from five countries with different fruit and vegetable intakes and reported rates of CVD. Eighty volunteers (forty males, forty females per centre), age range 25–45 years, were recruited from France, Northern Ireland, UK, Republic of Ireland, The Netherlands, and Spain, and their LDL composition and lag phase were measured. There were some differences in LDL carotenoid and α-tocopherol concentrations between countries. α-Tocopherol was low and β- + γ-tocopherol were high (P

AB - Within Europe there are differences in cardiovascular disease (CVD) risk between countries and this might be related to dietary habits. Oxidative modification of LDL is suggested to increase the risk of CVD and both the fatty acid and antioxidant content of LDL can affect its oxidation. In the present study, concentration of LDL fatty acid and antioxidant micronutrients (tocopherols and carotenoids) and ex vivo oxidative resistance of LDL (lag phase) was compared in volunteers from five countries with different fruit and vegetable intakes and reported rates of CVD. Eighty volunteers (forty males, forty females per centre), age range 25–45 years, were recruited from France, Northern Ireland, UK, Republic of Ireland, The Netherlands, and Spain, and their LDL composition and lag phase were measured. There were some differences in LDL carotenoid and α-tocopherol concentrations between countries. α-Tocopherol was low and β- + γ-tocopherol were high (P

U2 - 10.1079/BJN2001484

DO - 10.1079/BJN2001484

M3 - Article

SN - 0007-1145

VL - 87

SP - 21

EP - 29

JO - British Journal of Nutrition

JF - British Journal of Nutrition

IS - 1

ER -

Comparison of LDL fatty acid and carotenoid concentrations and oxidative resistance of LDL in volunteers from countries with different rates of cardiovascular disease

Abstract

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