Composite scaffolds for large bone defects

Evangelos Daskalakis; Enes Aslan; Fengyuan Liu; Glen Cooper; Andrew Weightman; Bahattin Koç; Gordon Blunn; P. J. Bartolo

doi:10.1007/978-3-030-29041-2_31

Composite scaffolds for large bone defects

Evangelos Daskalakis^*, Enes Aslan, Fengyuan Liu, Glen Cooper, Andrew Weightman, Bahattin Koç, Gordon Blunn, P. J. Bartolo

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

This paper investigates the use of polymer-ceramic composite scaffolds for bone regeneration. Different ratios between Poly-εcaprolactone (PCL) and Hydroxyapatite (HA) were considered. Scaffolds were produced using two different lay-down patterns (0/90° and 0/45°), and pore sizes (350 μm, 500 μm and 700 μm). Compressive and cell proliferation tests are reported. Human adipose derived stem cells (hADSCs) were used for the biological characterization.

Original language	English
Title of host publication	Progress in Digital and Physical Manufacturing - Proceedings of ProDPM 2019
Editors	Henrique A. Almeida, Joel C. Vasco
Publisher	Springer
Pages	250-257
Number of pages	8
ISBN (Electronic)	9783030290412
ISBN (Print)	9783030290405
DOIs	https://doi.org/10.1007/978-3-030-29041-2_31
Publication status	Published - 29 Sept 2019
Event	1st International Conference on Progress in Digital and Physical Manufacturing, ProDPM 2019 - Leiria, Portugal Duration: 2 Oct 2019 → 4 Oct 2019

Publication series

Name	Lecture Notes in Mechanical Engineering
ISSN (Print)	2195-4356
ISSN (Electronic)	2195-4364

Conference

Conference	1st International Conference on Progress in Digital and Physical Manufacturing, ProDPM 2019
Country/Territory	Portugal
City	Leiria
Period	2/10/19 → 4/10/19

Keywords

Additive manufacturing
Bioprinting
Hydroxyapatite
Tissue engineering
UKRI
EPSRC
EP/R01513/1

Access to Document

10.1007/978-3-030-29041-2_31

Cite this

Daskalakis, E., Aslan, E., Liu, F., Cooper, G., Weightman, A., Koç, B., Blunn, G., & Bartolo, P. J. (2019). Composite scaffolds for large bone defects. In H. A. Almeida, & J. C. Vasco (Eds.), Progress in Digital and Physical Manufacturing - Proceedings of ProDPM 2019 (pp. 250-257). (Lecture Notes in Mechanical Engineering). Springer. https://doi.org/10.1007/978-3-030-29041-2_31

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title = "Composite scaffolds for large bone defects",

abstract = "This paper investigates the use of polymer-ceramic composite scaffolds for bone regeneration. Different ratios between Poly-εcaprolactone (PCL) and Hydroxyapatite (HA) were considered. Scaffolds were produced using two different lay-down patterns (0/90° and 0/45°), and pore sizes (350 μm, 500 μm and 700 μm). Compressive and cell proliferation tests are reported. Human adipose derived stem cells (hADSCs) were used for the biological characterization.",

keywords = "Additive manufacturing, Bioprinting, Hydroxyapatite, Tissue engineering, UKRI, EPSRC, EP/R01513/1",

author = "Evangelos Daskalakis and Enes Aslan and Fengyuan Liu and Glen Cooper and Andrew Weightman and Bahattin Ko{\c c} and Gordon Blunn and Bartolo, {P. J.}",

note = "Funding Information: Acknowledgement. This project has been supported by the University of Manchester and the Engineering and Physical Sciences Research Council (EPSRC) of the UK, the Global Challenges Research Fund (CRF), grant number EP/R01513/1. Publisher Copyright: {\textcopyright} 2020, Springer Nature Switzerland AG.; 1st International Conference on Progress in Digital and Physical Manufacturing, ProDPM 2019 ; Conference date: 02-10-2019 Through 04-10-2019",

year = "2019",

month = sep,

day = "29",

doi = "10.1007/978-3-030-29041-2_31",

language = "English",

isbn = "9783030290405",

series = "Lecture Notes in Mechanical Engineering",

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pages = "250--257",

editor = "Almeida, {Henrique A.} and Vasco, {Joel C.}",

booktitle = "Progress in Digital and Physical Manufacturing - Proceedings of ProDPM 2019",

}

Daskalakis, E, Aslan, E, Liu, F, Cooper, G, Weightman, A, Koç, B, Blunn, G & Bartolo, PJ 2019, Composite scaffolds for large bone defects. in HA Almeida & JC Vasco (eds), Progress in Digital and Physical Manufacturing - Proceedings of ProDPM 2019. Lecture Notes in Mechanical Engineering, Springer, pp. 250-257, 1st International Conference on Progress in Digital and Physical Manufacturing, ProDPM 2019, Leiria, Portugal, 2/10/19. https://doi.org/10.1007/978-3-030-29041-2_31

Composite scaffolds for large bone defects. / Daskalakis, Evangelos; Aslan, Enes; Liu, Fengyuan et al.
Progress in Digital and Physical Manufacturing - Proceedings of ProDPM 2019. ed. / Henrique A. Almeida; Joel C. Vasco. Springer, 2019. p. 250-257 (Lecture Notes in Mechanical Engineering).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Composite scaffolds for large bone defects

AU - Daskalakis, Evangelos

AU - Aslan, Enes

AU - Liu, Fengyuan

AU - Cooper, Glen

AU - Weightman, Andrew

AU - Koç, Bahattin

AU - Blunn, Gordon

AU - Bartolo, P. J.

N1 - Funding Information: Acknowledgement. This project has been supported by the University of Manchester and the Engineering and Physical Sciences Research Council (EPSRC) of the UK, the Global Challenges Research Fund (CRF), grant number EP/R01513/1. Publisher Copyright: © 2020, Springer Nature Switzerland AG.

PY - 2019/9/29

Y1 - 2019/9/29

N2 - This paper investigates the use of polymer-ceramic composite scaffolds for bone regeneration. Different ratios between Poly-εcaprolactone (PCL) and Hydroxyapatite (HA) were considered. Scaffolds were produced using two different lay-down patterns (0/90° and 0/45°), and pore sizes (350 μm, 500 μm and 700 μm). Compressive and cell proliferation tests are reported. Human adipose derived stem cells (hADSCs) were used for the biological characterization.

AB - This paper investigates the use of polymer-ceramic composite scaffolds for bone regeneration. Different ratios between Poly-εcaprolactone (PCL) and Hydroxyapatite (HA) were considered. Scaffolds were produced using two different lay-down patterns (0/90° and 0/45°), and pore sizes (350 μm, 500 μm and 700 μm). Compressive and cell proliferation tests are reported. Human adipose derived stem cells (hADSCs) were used for the biological characterization.

KW - Additive manufacturing

KW - Bioprinting

KW - Hydroxyapatite

KW - Tissue engineering

KW - UKRI

KW - EPSRC

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DO - 10.1007/978-3-030-29041-2_31

M3 - Conference contribution

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SN - 9783030290405

T3 - Lecture Notes in Mechanical Engineering

SP - 250

EP - 257

BT - Progress in Digital and Physical Manufacturing - Proceedings of ProDPM 2019

A2 - Almeida, Henrique A.

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T2 - 1st International Conference on Progress in Digital and Physical Manufacturing, ProDPM 2019

Y2 - 2 October 2019 through 4 October 2019

ER -

Composite scaffolds for large bone defects

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