Composite scaffolds for large bone defects

Evangelos Daskalakis*, Enes Aslan, Fengyuan Liu, Glen Cooper, Andrew Weightman, Bahattin Koç, Gordon Blunn, P. J. Bartolo

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper investigates the use of polymer-ceramic composite scaffolds for bone regeneration. Different ratios between Poly-εcaprolactone (PCL) and Hydroxyapatite (HA) were considered. Scaffolds were produced using two different lay-down patterns (0/90° and 0/45°), and pore sizes (350 μm, 500 μm and 700 μm). Compressive and cell proliferation tests are reported. Human adipose derived stem cells (hADSCs) were used for the biological characterization.

Original languageEnglish
Title of host publicationProgress in Digital and Physical Manufacturing - Proceedings of ProDPM 2019
EditorsHenrique A. Almeida, Joel C. Vasco
PublisherSpringer
Pages250-257
Number of pages8
ISBN (Electronic)9783030290412
ISBN (Print)9783030290405
DOIs
Publication statusPublished - 29 Sept 2019
Event1st International Conference on Progress in Digital and Physical Manufacturing, ProDPM 2019 - Leiria, Portugal
Duration: 2 Oct 20194 Oct 2019

Publication series

NameLecture Notes in Mechanical Engineering
ISSN (Print)2195-4356
ISSN (Electronic)2195-4364

Conference

Conference1st International Conference on Progress in Digital and Physical Manufacturing, ProDPM 2019
Country/TerritoryPortugal
CityLeiria
Period2/10/194/10/19

Keywords

  • Additive manufacturing
  • Bioprinting
  • Hydroxyapatite
  • Tissue engineering
  • UKRI
  • EPSRC
  • EP/R01513/1

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