COVID-19: a promising cure for the global panic

Balachandar Vellingiri, Kaavya Jayaramayya, Mahalaxmi Iyer, Arul Narayanasamy, Vivekanandan Govindasamy, Bupesh Giridharan, Singaravelu Ganesan, Anila Venugopal, Dhivya Venkatesan, Harsha Ganesan, Kamarajan Rajagopalan, Ssang-Goo Cho, Nachimuthu Senthil Kumar, Mohana Devi Subramaniam , Pattanathu Rahman

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Abstract

The novel Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, which is the causative agent of a potentially fatal disease that is of great global public health concern. The outbreak of the new COVID-19 is wreaking havoc worldwide due to inadequate risk assessment regarding the urgency of the situation. The COVID-19 pandemic has entered a dangerous new phase. When compared with SARS and MERS, COVID-19 has spread more rapidly, due to increased globalization and adaptation of the virus in every environment. Slowing the spread of the COVID-19 cases will significantly reduce the strain on the healthcare system of the country by limiting the number of people who are severely sick by COVID-19 and need hospital care. Hence, the recent outburst of COVID-19 highlights an urgent need for therapeutics targeting SARS-CoV-2. Here, we have discussed the structure of virus; varying symptoms among COVID-19, SARS, MERS and the common flu; the probable mechanism behind the infection and its immune response. Further, the current treatment options, drugs available, ongoing trials and recent diagnostics for COVID-19 have been discussed. We suggest traditional Indian medicinal plants as possible novel therapeutic approaches, exclusively targeting SARS-CoV-2 and its pathways.
Original languageEnglish
Article number138277
JournalScience of the Total Environment
Early online date4 Apr 2020
DOIs
Publication statusEarly online - 4 Apr 2020

Keywords

  • COVID-19
  • Coronavirus
  • cure
  • medicinal plants
  • herb

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