Crystallization of bovine pancreatic polypeptide in the presence of crystalline diglycidyl ether of bisphenol A (Araldite): epitaxy or covalent nucleation?

S. P. Wood; Robert W. Janes; E. Sweeney; R. A. Palmer

doi:10.1016/0022-0248(92)90246-F

Crystallization of bovine pancreatic polypeptide in the presence of crystalline diglycidyl ether of bisphenol A (Araldite): epitaxy or covalent nucleation?

S. P. Wood, Robert W. Janes, E. Sweeney, R. A. Palmer

Institute of Life Sciences and Healthcare

Research output: Contribution to journal › Article › peer-review

Abstract

Bovine pancreatic polypeptide (bPP), a 36 residue peptide hormone with a stable folded structure in solution has been crystallized from aqueous solution in the presence of seed crystals derived from an ageing sample of commercial epoxy resin. X-ray analysis established these to be crystals of diglycidyl ether of bisphenol A (DGEBA). The possibility of epitaxial or covalent nucleation is discussed.

Original language	English
Pages (from-to)	204-207
Journal	Journal of Crystal Growth
Volume	122
Issue number	1-4
DOIs	https://doi.org/10.1016/0022-0248(92)90246-F
Publication status	Published - 1 Aug 1992

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title = "Crystallization of bovine pancreatic polypeptide in the presence of crystalline diglycidyl ether of bisphenol A (Araldite): epitaxy or covalent nucleation?",

abstract = "Bovine pancreatic polypeptide (bPP), a 36 residue peptide hormone with a stable folded structure in solution has been crystallized from aqueous solution in the presence of seed crystals derived from an ageing sample of commercial epoxy resin. X-ray analysis established these to be crystals of diglycidyl ether of bisphenol A (DGEBA). The possibility of epitaxial or covalent nucleation is discussed.",

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AU - Wood, S. P.

AU - Janes, Robert W.

AU - Sweeney, E.

AU - Palmer, R. A.

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N2 - Bovine pancreatic polypeptide (bPP), a 36 residue peptide hormone with a stable folded structure in solution has been crystallized from aqueous solution in the presence of seed crystals derived from an ageing sample of commercial epoxy resin. X-ray analysis established these to be crystals of diglycidyl ether of bisphenol A (DGEBA). The possibility of epitaxial or covalent nucleation is discussed.

AB - Bovine pancreatic polypeptide (bPP), a 36 residue peptide hormone with a stable folded structure in solution has been crystallized from aqueous solution in the presence of seed crystals derived from an ageing sample of commercial epoxy resin. X-ray analysis established these to be crystals of diglycidyl ether of bisphenol A (DGEBA). The possibility of epitaxial or covalent nucleation is discussed.

U2 - 10.1016/0022-0248(92)90246-F

DO - 10.1016/0022-0248(92)90246-F

M3 - Article

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JO - Journal of Crystal Growth

JF - Journal of Crystal Growth

IS - 1-4

ER -

Crystallization of bovine pancreatic polypeptide in the presence of crystalline diglycidyl ether of bisphenol A (Araldite): epitaxy or covalent nucleation?

Abstract

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