Discovery of novel UDP-N-Acetylglucosamine Acyltransferase (LpxA) inhibitors with activity against Pseudomonas aeruginosa

M. Dominic Ryan, Alastair L. Parkes, David Corbett, Anthony P. Dickie, Michelle Southey, Ole A. Andersen, Daniel B. Stein, Olivier R. Barbeau, Angelo Sanzone, Pia Thommes, John Barker, Ricky Cain, Christel Compper, Magali Dejob, Alain Dorali, Donnya Etheridge, Sian Evans, Adele Faulkner, Elise Gadouleau, Timothy GormanDenes Haase, Maisie Holbrow-wilshaw, Thomas Krulle, Xianfu Li, Christopher Lumley, Barbara Mertins, Spencer Napier, Rajesh Odedra, Kostas Papadopoulos, Vasileios Roumpelakis, Kate Spear, Emily Trimby, Jennifer Williams, Michael Zahn, Anthony D. Keefe, Ying Zhang, Holly T. Soutter, Paolo A. Centrella, Matthew A. Clark, John W. Cuozzo, Christoph E. Dumelin, Boer Deng, Avery Hunt, Eric A. Sigel, Dawn M. Troast, Boudewijn L. M. Dejonge

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Biochemistry, Genetics and Molecular Biology

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Pharmacology, Toxicology and Pharmaceutical Science