Generation of multi-layered structures for biomedical applications using a novel tri-needle co-axial device and electrohydrodynamic flow

Zeeshan Ahmad, H. Zhang, U. Farook, M. Edirisinghe, E. Stride, P. Colombo

    Research output: Contribution to journalArticlepeer-review

    Abstract

    In this short communication, we describe the scope and flexibility of using a novel device containing three coaxially arranged needles to form a variety of novel morphologies. Different combinations of materials are subjected to controlled flow through the device under the influence of an applied electric field. The resulting electrohydrodynamic flow allows us to prepare double-layered bubbles, porous encapsulated threads and nanocapsules containing three layers. The ability to process such multilayered structures is very significant for biomedical engineering applications, for example, generating capsules for drug delivery, which can provide multistage controlled release.
    Original languageEnglish
    Pages (from-to)1255-1261
    Number of pages7
    JournalJournal of the Royal Society Interface
    Volume5
    Issue number27
    DOIs
    Publication statusPublished - 2008

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