@inbook{fe8d6566447c4bf7aae1df90b914cb60,
title = "Genetic and metabolic aspects of primary and secondary metabolism of the zygomycetes",
abstract = "Basal lineages of the kingdom of fungi comprise terrestrial and aquatic fungi, which are traditionally summarized as Chytridiomycota and Zygomycota in a colloquial sense. The zygomycetes build up the most basal lineage among the terrestrial fungi. As the earliest fungi to conquer terrestrial habitats, they facilitated early coevolution with other land-dwelling microorganisms with implications on the primary and secondary metabolism which is adaptive to the life in soil. Advances in next-generation genome sequencing allow us to gain a new layer of knowledge with respect to their metabolism and its regulation. Recent revisions of the metabolic potential of zygomycetes using genome mining suggested a hidden potential for the production of secondary metabolites. First insights suggest a revision of our understanding of the importance and mode of action of metabolic pathways revealing a fascinating potential to produce novel natural compounds. The aim of this review is to draw attention to the zygomycetes as a unique fungal group and to inspire the scientific community to explore its potential as participants in complex ecosystems for innovative metabolic regulatory frameworks and novel compounds.",
keywords = "fumaric acid, carotenoid biosynthesis, mucor circinelloides, carotenoid biosynthesis gene, Rhizopus species",
author = "Kerstin Voigt and Thomas Wolf and Katrin Ochsenreiter and G{\'a}bor Nagy and Kerstin Kaerger and Ekaterina Shelest and Tam{\'a}s Papp",
year = "2016",
month = feb,
day = "20",
doi = "10.1007/978-3-319-27790-5_15",
language = "English",
isbn = "978-3-319-27788-2",
series = "The Mycota",
publisher = "Springer",
pages = "361--385",
editor = "Dirk Hoffmeister",
booktitle = "Biochemistry and Molecular Biology",
}
