Glass ionomer as an expander of allograft in revision arthroplasty of the hip

J D J Eldridge, J L Cunningham, A Samuels, G W Blunn, T J Lawes, I D Learmonth, A E Goodship

Research output: Contribution to journalArticlepeer-review

Abstract

The use of glass ionomer as a bone graft expander was investigated in an in vivo model of revision hip arthroplasty. Bone grafts of pure allograft and allograft + glass ionomer particles in a 50:50 by weight mixture were implanted in an ovine hemi-arthroplasty model. Post-operative assessments of locomotor function, radiographic appearance and quantitative changes in mineralisation around the graft were made at 2, 4 and 6 months. Post-mortem assessments of radiographic and histologic appearance of the grafts were made at 6 months. No significant differences were noted in any of the measured or assessed parameters between the two graft types. The glass ionomer particles seemed to be well tolerated within the matrix of new bone, smaller sized particles appearing to be better incorporated than larger ones. The use of particles of glass ionomer as a bone graft expander, in this in vivo model of revision hip arthroplasty, would therefore appear to offer no detriment in performance over pure allograft in the short to medium term.

Original languageEnglish
Pages (from-to)499-508
Number of pages10
JournalBiomaterials
Volume24
Issue number3
DOIs
Publication statusPublished - Feb 2003

Keywords

  • Acrylic Resins
  • Animals
  • Arthroplasty, Replacement, Hip
  • Biocompatible Materials
  • Bone Density
  • Bone Transplantation
  • Hip
  • Hip Prosthesis
  • Male
  • Radiography
  • Sheep
  • Silicon Dioxide
  • Time Factors
  • Research Support, Non-U.S. Gov't

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