Guidance and standard operating procedures for functional exercise testing in cystic fibrosis

Zoe Saynor, Mathieu Gruet, Melitta A. McNarry, Brenda Button, Lisa Morrison, Marlies Wagner, Abbey Sawyer, H. Hebestreit, Thomas Radtke, Don S. Urquhart

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Regular exercise testing is recommended for all people with cystic fibrosis (pwCF). A range of validated tests, which integrate both strength and aerobic function, are available and increasingly being used. Together, these tests offer the ability for comprehensive exercise evaluation. Extensive research and expert consensus over recent years has enabled the adaptation and standardisation of a range of exercise tests to aid the understanding of the pathophysiology related to exercise limitation in pwCF, and has led to the development of novel exercise tests which may be applied to pwCF. This article provides expert, opinion-based clinical practice guidance, along with test instructions, for a selection of commonly used valid tests which have documented clinimetric properties for pwCF. Importantly, this document also highlights previously used tests that are no longer suggested for pwCF and areas where research is mandated. This collaboration, on behalf of the European CF Society Exercise Working Group, represents expert consensus by a multidisciplinary panel of physiotherapists, exercise scientists and clinicians and aims to improve global standardisation of functional exercise testing of pwCF. In short, the standardised use of a small selection of tests performed to a high standard is advocated.
Original languageEnglish
Article number230029
Number of pages18
JournalEuropean Respiratory Review
Issue number169
Publication statusPublished - 9 Aug 2023

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