Hydrogels in mucosal delivery

H. Nazar, Marta Roldo, D. Fatouros, Marisa Van der Merwe, John Tsibouklis

Research output: Contribution to journalArticlepeer-review


The concept of mucoadhesion and the molecular design requirements for the synthesis of mucoadhesive agents are both well understood and, as a result, hydrogel formulations that may be applied to mucosal surfaces are readily accessible. Nanosized hydrogel systems that make use of biological recognition or targeting motifs, by reacting to disease-specific environmental triggers and/or chemical signals to affect drug release, are now emerging as components of a new generation of therapeutics that promise improved residence time, faster response to stimuli and triggered release.
Original languageEnglish
Pages (from-to)535-555
Number of pages21
JournalTherapeutic Delivery
Issue number4
Publication statusPublished - Apr 2012


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