Influence of increased fruit and vegetable intake on plasma and lipoprotein carotenoids and LDL oxidation in smokers and nonsmokers

Mridula Chopra, M. O'Neill, N. Keogh, G. Wortley, S. Southon, D. Thurnham

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Background: Epidemiological studies suggest a cardioprotective role for carotenoid-rich foods. Smokers have a high risk of cardiovascular disease and low dietary intake and plasma concentrations of carotenoids. The aim of this study was to determine the carotenoid response of smokers and nonsmokers to increased intake of 300–400 g of vegetables and its effect on LDL oxidation. Methods: After a depletion period of 8 days, 34 healthy females (18 nonsmokers, 16 smokers) were supplemented with β-carotene- and lutein-rich (green) and lycopene-rich (red) vegetable foods, each for 7 days. Results: Baseline concentrations (mean ± SD) of plasma β-carotene (0.203 ± 0.28 μmol/L vs 0.412 ± 0.34 μmol/L; P
    Original languageEnglish
    Pages (from-to)1818-1829
    Number of pages12
    JournalClinical Chemistry
    Volume46
    Issue number11
    Publication statusPublished - Nov 2000

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