Influence of increased fruit and vegetable intake on plasma and lipoprotein carotenoids and LDL oxidation in smokers and nonsmokers

Mridula Chopra; M. O'Neill; N. Keogh; G. Wortley; S. Southon; D. Thurnham

Influence of increased fruit and vegetable intake on plasma and lipoprotein carotenoids and LDL oxidation in smokers and nonsmokers

Mridula Chopra, M. O'Neill, N. Keogh, G. Wortley, S. Southon, D. Thurnham

School of Pharmacy & Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Background: Epidemiological studies suggest a cardioprotective role for carotenoid-rich foods. Smokers have a high risk of cardiovascular disease and low dietary intake and plasma concentrations of carotenoids. The aim of this study was to determine the carotenoid response of smokers and nonsmokers to increased intake of 300–400 g of vegetables and its effect on LDL oxidation. Methods: After a depletion period of 8 days, 34 healthy females (18 nonsmokers, 16 smokers) were supplemented with β-carotene- and lutein-rich (green) and lycopene-rich (red) vegetable foods, each for 7 days. Results: Baseline concentrations (mean ± SD) of plasma β-carotene (0.203 ± 0.28 μmol/L vs 0.412 ± 0.34 μmol/L; P

Original language	English
Pages (from-to)	1818-1829
Number of pages	12
Journal	Clinical Chemistry
Volume	46
Issue number	11
Publication status	Published - Nov 2000

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title = "Influence of increased fruit and vegetable intake on plasma and lipoprotein carotenoids and LDL oxidation in smokers and nonsmokers",

abstract = "Background: Epidemiological studies suggest a cardioprotective role for carotenoid-rich foods. Smokers have a high risk of cardiovascular disease and low dietary intake and plasma concentrations of carotenoids. The aim of this study was to determine the carotenoid response of smokers and nonsmokers to increased intake of 300–400 g of vegetables and its effect on LDL oxidation. Methods: After a depletion period of 8 days, 34 healthy females (18 nonsmokers, 16 smokers) were supplemented with β-carotene- and lutein-rich (green) and lycopene-rich (red) vegetable foods, each for 7 days. Results: Baseline concentrations (mean ± SD) of plasma β-carotene (0.203 ± 0.28 μmol/L vs 0.412 ± 0.34 μmol/L; P ",

author = "Mridula Chopra and M. O'Neill and N. Keogh and G. Wortley and S. Southon and D. Thurnham",

year = "2000",

month = nov,

language = "English",

volume = "46",

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journal = "Clinical Chemistry",

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publisher = "American Association for Clinical Chemistry Inc.",

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TY - JOUR

T1 - Influence of increased fruit and vegetable intake on plasma and lipoprotein carotenoids and LDL oxidation in smokers and nonsmokers

AU - Chopra, Mridula

AU - O'Neill, M.

AU - Keogh, N.

AU - Wortley, G.

AU - Southon, S.

AU - Thurnham, D.

PY - 2000/11

Y1 - 2000/11

N2 - Background: Epidemiological studies suggest a cardioprotective role for carotenoid-rich foods. Smokers have a high risk of cardiovascular disease and low dietary intake and plasma concentrations of carotenoids. The aim of this study was to determine the carotenoid response of smokers and nonsmokers to increased intake of 300–400 g of vegetables and its effect on LDL oxidation. Methods: After a depletion period of 8 days, 34 healthy females (18 nonsmokers, 16 smokers) were supplemented with β-carotene- and lutein-rich (green) and lycopene-rich (red) vegetable foods, each for 7 days. Results: Baseline concentrations (mean ± SD) of plasma β-carotene (0.203 ± 0.28 μmol/L vs 0.412 ± 0.34 μmol/L; P

AB - Background: Epidemiological studies suggest a cardioprotective role for carotenoid-rich foods. Smokers have a high risk of cardiovascular disease and low dietary intake and plasma concentrations of carotenoids. The aim of this study was to determine the carotenoid response of smokers and nonsmokers to increased intake of 300–400 g of vegetables and its effect on LDL oxidation. Methods: After a depletion period of 8 days, 34 healthy females (18 nonsmokers, 16 smokers) were supplemented with β-carotene- and lutein-rich (green) and lycopene-rich (red) vegetable foods, each for 7 days. Results: Baseline concentrations (mean ± SD) of plasma β-carotene (0.203 ± 0.28 μmol/L vs 0.412 ± 0.34 μmol/L; P

M3 - Article

SN - 0009-9147

VL - 46

SP - 1818

EP - 1829

JO - Clinical Chemistry

JF - Clinical Chemistry

IS - 11

ER -

Influence of increased fruit and vegetable intake on plasma and lipoprotein carotenoids and LDL oxidation in smokers and nonsmokers

Abstract

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