This study examined the impact of information and communication technology (ICT) on unemployment among the countries in West Africa Monetary Zones (WAMZ) for the period 2005–2020. The study engaged the data sourced from World Bank Development Indicators (WDI), International labour organisation (ILO) and International Telecommunication Union (ITU). The study estimated the fixed and random effect models and pooled mean group estimators. The results indicate a negative and significant effect of ICT adoption on unemployment among countries of WAMZ. On the other hand, the magnitude of the effects differs, depending on the indicator of ICT being examined.