Intestine-specific, oral delivery of captopril/ montmorillonite: Formulation and release kinetics

Madurai Suguna Lakshmi, Stella Winnarasi Joseph, Asit Baran Mandal, John Tsibouklis, Boreddy S R Reddy

Research output: Contribution to journalArticlepeer-review

Abstract

The intercalation of captopril (CP) into the interlayers of montmorillonite (MMT) affords an intestine-selective drug delivery system that has a captopril-loading capacity of up to ca. 14%w/w and which exhibits near-zero-order release kinetics.

Original languageEnglish
Article number15
Pages (from-to)1-8
Number of pages8
JournalNanoscale Research Letters
Volume7
DOIs
Publication statusPublished - 26 Jan 2012

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