Linker length modulates DNA cross-linking reactivity and cytotoxic potency of C8/C8‘ ether-linked C2-exo-unsaturated pyrrolo[2,1-c][1,4]benzodiazepine (PBD) dimers

S. Gregson, Phillip W. Howard, D. Gullick, A. Hamaguchi, K. Corcoran, Natalie A. Brooks, J. Hartley, T. Jenkins, Sejal Patel, Matt Guille, D. Thurston

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Biochemistry, Genetics and Molecular Biology

Pharmacology, Toxicology and Pharmaceutical Science