Meroditerpenoids and derivatives from the brown alga Cystoseira baccata and their antifouling properties

R. Mokrini, M. Ben Mesaoud, M. Daoudi, Claire Hellio, J. Marechal, M. El-Hattab, A. Ortalo-Magne, L. Piovetti, G. Culioli

Research output: Contribution to journalArticlepeer-review

Abstract

The brown alga Cystoseira baccata harvested along the Atlantic coasts of Morocco yielded seven new meroditerpenoids (1-4) and derivatives (5-7), whose chemical structures were elucidated mainly by 2D NMR and mass spectrometry. Surprisingly, for all these compounds, which possess a bicyclo[4.3.0]nonane ring system, a trans fusion of the bicyclic system was deduced by stereochemical studies even though such compounds isolated from Cystoseira species are known to have a typical cis orientation for the bridgehead methyls. ne antifouling and antibacterial activities of compounds 1-5 and 7 were evaluated, as well as their toxicity toward nontarget species. Compounds 4, 5, and 7 showed antifouling activities against growth of microalgae, macroalgal settlement, and mussel phenoloxidase activity, while being nontoxic to larvae of sea urchins and oysters.
Original languageEnglish
Pages (from-to)1806-1811
Number of pages6
JournalJournal of Natural Products
Volume71
Issue number11
DOIs
Publication statusPublished - 2008

Fingerprint

Dive into the research topics of 'Meroditerpenoids and derivatives from the brown alga Cystoseira baccata and their antifouling properties'. Together they form a unique fingerprint.

Cite this