Modelling the rate-dependent mechanical behaviour of the brain tissue

Afshin Anssari-Benam, Giuseppe Saccomandi

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A new modelling approach is employed in this work for application to the rate-dependent mechanical behaviour of the brain tissue, as an incompressible isotropic material. Extant datasets encompassing single- and multi-mode compression, tension and simple shear deformation(s) are considered, across a wide range of deformation rates from quasi-static to rates akin to blast loading conditions, in the order of 1000 s−1 . With a simple functional form and a reduced number of parameters, the model is shown to capture the considered rate-dependent behaviours favourably, including in both single- and multi-mode deformation fits, and over all range of deformation rates. The provided modelling results here are obtained from either first fitting the model to the quasi-static data, or/and predicting the behaviour at a different rate than those used for calibrating the model parameters. Given its simplicity, versatility, predictive capability and accuracy, the application of the utilised modelling framework in this work to the rate-dependent mechanical behaviour of the brain tissue is proposed.
Original languageEnglish
Article number106502
Number of pages12
JournalJournal of the Mechanical Behavior of Biomedical Materials
Early online date19 Mar 2024
Publication statusEarly online - 19 Mar 2024


  • Brain tissue
  • Rate-dependency
  • Constitutive modelling
  • Pseudo-hyperelasticity
  • A comprehensive model

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