Negative centralisation of HIV/AIDS trauma and health-related quality of life: do post-traumatic stress symptoms explain the link?

Desmond Uchechukwu Onu, Steven Kator Iorfa, Dorothy I. Ugwu*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review


    Over-integration of HIV-related trauma into the client’s memory in a negative emotional valence could be a serious health debilitating process which may result in negative post-traumatic health outcomes, affecting health-related quality of life (HRQoL) of people living with HIV (PLWH). We hypothesized that post-traumatic stress disorder (PTSD) symptoms are the mediating link between negative event centrality (NEC) and HRQoL among PLWH. Nine hundred and sixty-nine PLWH in Nigeria completed measures of NEC, PTSD symptoms and HRQoL. Model 4 of Hayes’ regression-based PROCESS macro version 3.0 for SPSS was employed to investigate relationships between variables of interest. NEC was positively associated with all domains of HRQoL. PLWH who had high negatively centralized identity on HIV also had high scores on PTSD symptoms. PTSD symptoms were also positively associated with all domains of HRQoL. PTSD symptoms also mediated the relationship between NEC and all domains of HRQoL. Assessing and treating PTSD symptoms among PLWH by clinicians could be helpful in enhancing HRQoL.

    Original languageEnglish
    Pages (from-to)206-213
    Number of pages8
    JournalAfrican Journal of AIDS Research
    Issue number3
    Publication statusPublished - 5 Sept 2020


    • centrality of event
    • health outcome
    • mediation
    • valence
    • well-being

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