Oral delivery of hydrophilic drugs to the brain

Ijeoma F Uchegbu (Inventor), Andreas Schatzlein (Inventor), Aikaterina Lalatsa (Inventor)

Research output: Patent

Abstract

(EN)A composition comprising a lipophilic derivative of a hydrophilic drug and an amphiphile compound for use in therapy wherein the composition is orally administered to the human or animal body. The invention includes derivatives such as palmitoylated Leucine[5]-Enkephalin and is useful in the treatment of schizophrenia, obsesity, pain and sleep disorders, psychiatric diseases, neurodegenerative conditions, brain cancers and infective diseases.
Original languageEnglish
Patent numberPCT/GB2010/050355
Publication statusPublished - 10 Sept 2010

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