Oral delivery of hydrophilic drugs to the brain

Ijeoma F Uchegbu; Andreas Schatzlein; Aikaterina Lalatsa

Oral delivery of hydrophilic drugs to the brain

Ijeoma F Uchegbu (Inventor), Andreas Schatzlein (Inventor), Aikaterina Lalatsa (Inventor)

School of Pharmacy & Biomedical Sciences

University College London

Research output: Patent

Abstract

(EN)A composition comprising a lipophilic derivative of a hydrophilic drug and an amphiphile compound for use in therapy wherein the composition is orally administered to the human or animal body. The invention includes derivatives such as palmitoylated Leucine[5]-Enkephalin and is useful in the treatment of schizophrenia, obsesity, pain and sleep disorders, psychiatric diseases, neurodegenerative conditions, brain cancers and infective diseases.

Original language	English
Patent number	PCT/GB2010/050355
Publication status	Published - 10 Sep 2010

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Cite this

@misc{7d5d14cc78c4481fa754f7b0eae0ea7b,

title = "Oral delivery of hydrophilic drugs to the brain",

abstract = "(EN)A composition comprising a lipophilic derivative of a hydrophilic drug and an amphiphile compound for use in therapy wherein the composition is orally administered to the human or animal body. The invention includes derivatives such as palmitoylated Leucine[5]-Enkephalin and is useful in the treatment of schizophrenia, obsesity, pain and sleep disorders, psychiatric diseases, neurodegenerative conditions, brain cancers and infective diseases.",

author = "Uchegbu, {Ijeoma F} and Andreas Schatzlein and Aikaterina Lalatsa",

year = "2010",

month = sep,

day = "10",

language = "English",

type = "Patent",

note = "PCT/GB2010/050355",

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TY - PAT

T1 - Oral delivery of hydrophilic drugs to the brain

AU - Uchegbu, Ijeoma F

AU - Schatzlein, Andreas

AU - Lalatsa, Aikaterina

PY - 2010/9/10

Y1 - 2010/9/10

N2 - (EN)A composition comprising a lipophilic derivative of a hydrophilic drug and an amphiphile compound for use in therapy wherein the composition is orally administered to the human or animal body. The invention includes derivatives such as palmitoylated Leucine[5]-Enkephalin and is useful in the treatment of schizophrenia, obsesity, pain and sleep disorders, psychiatric diseases, neurodegenerative conditions, brain cancers and infective diseases.

AB - (EN)A composition comprising a lipophilic derivative of a hydrophilic drug and an amphiphile compound for use in therapy wherein the composition is orally administered to the human or animal body. The invention includes derivatives such as palmitoylated Leucine[5]-Enkephalin and is useful in the treatment of schizophrenia, obsesity, pain and sleep disorders, psychiatric diseases, neurodegenerative conditions, brain cancers and infective diseases.

M3 - Patent

M1 - PCT/GB2010/050355

ER -

Oral delivery of hydrophilic drugs to the brain

Abstract

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