Osteointegration of hydroxyapatite-coated collars in cemented massive endoprostheses following revision surgery

B. Davies*, R. Kaila, L. Andritsos, C. Gray Stephens, G. W. Blunn, C. Gerrand, P. Gikas, A. Johnston

*Corresponding author for this work

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Aims Hydroxyapatite (HA)-coated collars have been shown to reduce aseptic loosening of massive endoprostheses following primary surgery. Limited information exists about their effectiveness in revision surgery. The aim of this study was to radiologically assess osteointegration to HA-coated collars of cemented massive endoprostheses following revision surgery. Methods Retrospective review of osseointegration frequency, pattern, and timing to a specific HA-coated collar on massive endoprostheses used in revision surgery at our tertiary referral centre between 2010 to 2017 was undertaken. Osseointegration was radiologically classified on cases with a minimum follow-up of six months. Results In all, 39 patients underwent radiological review at mean 43.5 months; 22/39 (56.4%) showed no osseointegration to the collar. Revision endoprostheses for aseptic loosening were less likely to show osseointegration compared with other indications for revision. Oncological cases with previous or current infection were more likely to show osseointegration to ≥ 1 collar side than those without evidence of prior infection. Conclusion This seven-year review identified osseointegration of HA-coated collars after revision surgery is less likely (43.6%, 17/39) than after primary surgery. Young patients who undergo revision surgery following initial oncological indication may benefit the most from this collar design. Use in revision oncological cases with a history of infection may be beneficial. HA-coated collars showed limited benefit for patients undergoing revision for failed arthroplasty with history of infection.

Original languageEnglish
Pages (from-to)371-379
Number of pages9
JournalBone and Joint Open
Issue number6
Publication statusPublished - 15 Jun 2021


  • Bone Tumour
  • Hydroxyapatite
  • Joint Reconstruction
  • Massive Endoprosthesis
  • Osteointegration
  • Sarcoma

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