Peripheral thermal responses in normal and cold-sensitive individuals to sublingual Glyceryl Trinitrate (GTN)

Katrina Hope, Clare M Eglin, Frank Golden, Michael J Tipton

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    Abstract

    Non-freezing cold injury (NFCI) is caused by prolonged exposure of the extremities to cold. The long-term sequelae of NFCI, include cold-sensitivity and pain[1]. The cold sensitivity is characterised by a reduction in basal skin blood flow and augmented vasoconstriction during cold exposure. We tested the hypothesis that sublingual GTN would increase blood flow in the peripheral microcirculation during and after a mild cold challenge in individuals who had not been diagnosed with NFCI, but were cold-sensitive.
    Original languageEnglish
    Article numberA34
    Pages (from-to)A34
    JournalExtreme Physiology & Medicine
    Volume4
    Issue numberSuppl 1
    DOIs
    Publication statusPublished - 14 Sept 2015
    Event15th International Conference on Environmental Ergonomics - Portsmouth, United Kingdom
    Duration: 28 Jun 20153 Jul 2015

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