Peripheral thermal responses in normal and cold-sensitive individuals to sublingual Glyceryl Trinitrate (GTN)

Katrina Hope; Clare M Eglin; Frank Golden; Michael J Tipton

doi:10.1186/2046-7648-4-S1-A34

Peripheral thermal responses in normal and cold-sensitive individuals to sublingual Glyceryl Trinitrate (GTN)

Katrina Hope, Clare M Eglin, Frank Golden, Michael J Tipton

University of Bristol

Research output: Contribution to journal › Meeting Abstract › peer-review

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Abstract

Non-freezing cold injury (NFCI) is caused by prolonged exposure of the extremities to cold. The long-term sequelae of NFCI, include cold-sensitivity and pain[1]. The cold sensitivity is characterised by a reduction in basal skin blood flow and augmented vasoconstriction during cold exposure. We tested the hypothesis that sublingual GTN would increase blood flow in the peripheral microcirculation during and after a mild cold challenge in individuals who had not been diagnosed with NFCI, but were cold-sensitive.

Original language	English
Article number	A34
Pages (from-to)	A34
Journal	Extreme Physiology & Medicine
Volume	4
Issue number	Suppl 1
DOIs	https://doi.org/10.1186/2046-7648-4-S1-A34
Publication status	Published - 14 Sept 2015
Event	15th International Conference on Environmental Ergonomics - Portsmouth, United Kingdom Duration: 28 Jun 2015 → 3 Jul 2015

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title = "Peripheral thermal responses in normal and cold-sensitive individuals to sublingual Glyceryl Trinitrate (GTN)",

abstract = "Non-freezing cold injury (NFCI) is caused by prolonged exposure of the extremities to cold. The long-term sequelae of NFCI, include cold-sensitivity and pain[1]. The cold sensitivity is characterised by a reduction in basal skin blood flow and augmented vasoconstriction during cold exposure. We tested the hypothesis that sublingual GTN would increase blood flow in the peripheral microcirculation during and after a mild cold challenge in individuals who had not been diagnosed with NFCI, but were cold-sensitive.",

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T1 - Peripheral thermal responses in normal and cold-sensitive individuals to sublingual Glyceryl Trinitrate (GTN)

AU - Hope, Katrina

AU - Eglin, Clare M

AU - Golden, Frank

AU - Tipton, Michael J

PY - 2015/9/14

Y1 - 2015/9/14

N2 - Non-freezing cold injury (NFCI) is caused by prolonged exposure of the extremities to cold. The long-term sequelae of NFCI, include cold-sensitivity and pain[1]. The cold sensitivity is characterised by a reduction in basal skin blood flow and augmented vasoconstriction during cold exposure. We tested the hypothesis that sublingual GTN would increase blood flow in the peripheral microcirculation during and after a mild cold challenge in individuals who had not been diagnosed with NFCI, but were cold-sensitive.

AB - Non-freezing cold injury (NFCI) is caused by prolonged exposure of the extremities to cold. The long-term sequelae of NFCI, include cold-sensitivity and pain[1]. The cold sensitivity is characterised by a reduction in basal skin blood flow and augmented vasoconstriction during cold exposure. We tested the hypothesis that sublingual GTN would increase blood flow in the peripheral microcirculation during and after a mild cold challenge in individuals who had not been diagnosed with NFCI, but were cold-sensitive.

U2 - 10.1186/2046-7648-4-S1-A34

DO - 10.1186/2046-7648-4-S1-A34

M3 - Meeting Abstract

SN - 2046-7648

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SP - A34

JO - Extreme Physiology & Medicine

JF - Extreme Physiology & Medicine

IS - Suppl 1

M1 - A34

T2 - 15th International Conference on Environmental Ergonomics

Y2 - 28 June 2015 through 3 July 2015

ER -

Peripheral thermal responses in normal and cold-sensitive individuals to sublingual Glyceryl Trinitrate (GTN)

Abstract

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