Preoperative DTI and probabilistic tractography in an amputee with deep brain stimulation for lower limb stump pain

S. Owen, J. Heath, M. Kringelbach, J. Stein, T. Aziz

    Research output: Contribution to journalArticlepeer-review

    Abstract

    This study aimed to find out whether preoperative diffusion tensor imaging (DTI) and probabilistic tractography could help with surgical planning for deep brain stimulation in the periaqueductal/periventricular grey area (PAG/PVG) in a patient with lower leg stump pain. A preoperative DTI was obtained from the patient, who then received DBS surgery in the PAG/PVG area with good pain relief. The postoperative MRI scan showing electrode placement was used to calculate four seed areas to represent the contacts on the Medtronic 3387® electrode. Probabilistic tractography was then performed from the pre-operative DTI image. Tracts were seen to connect to many areas within the pain network from the four different contacts. These initial findings suggest that preoperative DTI scanning and probabilistic tractography may be able to assist surgical planning in the future.
    Original languageEnglish
    Pages (from-to)485-490
    Number of pages6
    JournalBritish Journal of Neurosurgery
    Volume21
    Issue number5
    DOIs
    Publication statusPublished - Oct 2007

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