Prototropic tautomerism in unsymmetrically substituted 2,6- dihydroxypyridines

Eugen Barbu*, Corina Toader, Ion Bolocan, Flavian Cuiban

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Tautomerism of 3-R-2,6-dihydroxy-4-methylpyridine, where R = CN, COOH, was studied by FTIR and UV, in both solid state and different solvents. It was found that the hydroxypyridonic form is the predominant tautomer in most cases, while the interaction with solvents has a limited influence upon the nature and ratio of the other existing tautomers.

Original languageEnglish
Pages (from-to)794-798
Number of pages5
JournalRevista de Chimie
Issue number12
Publication statusPublished - 1 Dec 2002


  • Dihydroxypyridines
  • Hydrogen bonds
  • Tautomerism


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