Retinal vessel measurement: comparison between observer and computer driven methods

Richard S. B. Newsom*, Paul M. Sullivan, Sal M. B. Rassam, Roger Jagoe, Eva M. Kohner

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


A method of semi-automated image analysis for the measurement of retinal vessel diameters is described. This was compared with an observer-driven method for reproducibility and accuracy. The coefficient of variation for the data from the semi-automated method was 1.5-7.5% (depending on the vessel diameter) compared to 6-34% with the observer-driven method. The mean vessel diameters using the observer-driven method tended to be higher; however, this did not reach significance. The speed and low inter- and intra-observer variability for the semi-automated method make it a useful technique for measuring retinal blood vessel diameters. A larger variability was found between photographs taken at different times. This may be due to changes in retinal vessel diameter with changes in retinal perfusion pressure during the cardiac cycle.

Original languageEnglish
Pages (from-to)221-225
Number of pages5
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Issue number3
Publication statusPublished - 1 May 1992


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