Sealing the acetabular bone-implant interface against wear particle migration

M. J. Coathup*, J. Blackburn, T. J. Smith, A. E. Goodship, G. W. Blunn

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution


The impact of uncemented acetabular interfaces at resisting progressive osteolysis through bone attachment and the formation of a biological seal was investigated. Total hip replacements (THR) surgery was performed in an ovine model. Femoral heads were roughened to generate wear debris and aseptic loosening of the acetabular component. The specimens were analyzed radiographically, histologically and using scanning electron microscopy (SEM). Light microscopy of thin sections in all groups revealed the common mechanism of loosening involving a resorption wedge at the interface with progressive bone loss.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
Publication statusPublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 17 May 200421 May 2004


ConferenceTransactions - 7th World Biomaterials Congress


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