Simulating metal implants in full thickness cartilage defects

Krishnagoud Manda, Anders Eriksson

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Damage or degeneration in the articular cartilage is a major problem that affects millions of people in the world. The biomechanical forces at a site of damage in the cartilage may make the tissue more susceptible to continued long-term degeneration. Various biological treatments are currently available, but all have drawbacks. Alternatively, a contoured articular resurfacing implant is developed to offer a treatment to such full thickness chondral defects [1,3,4]. The main goal of using metal implants, to fill the degenerated portion of the cartilage, is to seal the surrounding cartilage so that further damage can be prevented, and to re-establish the integrity of the joint articulating surface. Many researchers have studied the safety, feasibility and reliability of the metal implants in animal models from a biological point of view [3,4]. They showed promising results. Till date, the mechanical behavior of cartilages surrounding the implant has not been studied, even in animal models. It is essential to understand the time dependent behavior of the cartilages due to biphasic nature of cartilage. Any protrusion of metal implant into the joint cavity damages the opposing soft tissue [1]. In order to avoid this, the positioning of implant together with the behavior of the cartilages immediately surrounding the implant have to be studied.
Original languageEnglish
Title of host publicationASME 2011 Summer Bioengineering Conference, SBC 2011
PublisherAmerican Society of Mechanical Engineers
Number of pages2
ISBN (Print)978-0791854587
Publication statusPublished - 2011
Externally publishedYes
EventASME 2011 Summer Bioengineering Conference, SBC 2011 - Farmington, PA, United States
Duration: 22 Jun 201125 Jun 2011


ConferenceASME 2011 Summer Bioengineering Conference, SBC 2011
Country/TerritoryUnited States
CityFarmington, PA


  • metals
  • thickness
  • cartilage


Dive into the research topics of 'Simulating metal implants in full thickness cartilage defects'. Together they form a unique fingerprint.

Cite this