Size does matter: sterically demanding metallocene-substituted 3-methylidene-oxindoles exhibit poor kinase inhibitory action

Chemistry

• Metallocene 100%
• Oxindole 100%
• Cytotoxicity 33%
• % Inhibition 33%
• Knoevenagel Condensation 33%
• Reaction Yield 33%
• Cobalt 33%
• Particle Size 33%
• Mixture 33%
• Microwave 33%

INIS

• kinases 66%
• size 33%
• yields 33%
• mixtures 33%
• inhibition 33%
• toxicity 33%
• cobalt 33%
• leukemia 33%
• microwave radiation 33%