Study of coagulation disorders and the prevalence of their related symptoms among COVID-19 patients in Al-Jouf Region, Saudi Arabia during the COVID-19 pandemic

Heba Bassiony Ghanem, Abozer Y. Elderdery, Hana Nassar Alnassar, Hadeel Ali Aldandan, Wajd Hamed Alkhaldi, Kholod Saad Alfuhygy, Mjd Muharib Alruwyli, Razan Ayed Alayyaf, Shoug Khaled Alkhalef, Saud Nahar L. Alruwaili, Jeremy Mills

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Introduction: The coronavirus (COVID-19) has affected millions of people around the world. COVID-19 patients, particularly those with the critical illness, have coagulation abnormalities, thrombocytopenia, and a high prevalence of intravascular thrombosis. Objectives: This work aims to assess the prevalence of coagulation disorders and their related symptoms among COVID-19 patients in the Al-Jouf region of Saudi Arabia. Subjects and methods: We conducted a retrospective study on 160 COVID-19 patients. Data were collected from the medical records department of King Abdulaziz Specialist Hospital, Sakaka, Al-Jouf, Saudi Arabia. The socio-demographic data, risk factors, coagulation profile investigation results, symptom and sign data related to coagulation disorders, and disease morbidity and mortality for COVID-19 patients were extracted from medical records, and the data were stored confidentially. Results: Males represented the highest prevalence of COVID-19 infection at 65%; 29% were aged 60 or over; 28% were smokers; and 36% were suffering from chronic diseases, with diabetes mellitus representing the highest prevalence. Positive D-dimer results occurred in 29% of cases, with abnormal platelet counts in 26%. Conclusion: Our findings confirm that the dysregulation of the coagulation cascade and the subsequent occurrence of coagulation disorders are common in coronavirus infections. The results show absolute values, not increases over normal values; thus, it is hard to justify increased risk and presence based on the presented data.
Original languageEnglish
Article number1085
Number of pages12
Issue number6
Publication statusPublished - 13 Mar 2023


  • COVID-19
  • coagulation disorders
  • D-dimer
  • SARS-CoV-2
  • symptoms

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